Protein Alignment AdipoR and PAQR8

DIOPT Version :10

• Sequence 1: NP_651061.1
• Gene: AdipoR / 42656
• FlyBaseID: FBgn0038984
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_588608.1
• Gene: PAQR8 / 85315
• HGNCID: 15708
• Length: 354
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 73/302 - (24%)
• Similarity: 122/302 - (40%)
• Gaps: 46/302 - (15%)

  Fly   167 KNLPKWLQD-------------------NDFLHRGHRPPLPSFRACFKSIFRVHTETGNIWTHLL 212
            :.|||.|:|                   ..::..|:||....:|..|.|:|:.|.|..|:|||||
Human    20 RRLPKILEDGLPKMPCTVPETDVPQLFREPYIRTGYRPTGHEWRYYFFSLFQKHNEVVNVWTHLL 84

  Fly   213 GCIAFIGVALYFISRPSVEIQTQEKIVFGAFFIGAIVCLGFSFAFHTLSCHSVEMGRLFSKLDYC 277
            ..:|.:.....|....::...:...:....|.:.:|..|..|...|.|...|......|..:||.
Human    85 AALAVLLRFWAFAEAEALPWASTHSLPLLLFILSSITYLTCSLLAHLLQSKSELSHYTFYFVDYV 149

  Fly   278 GIALLIMGSFVPWLYY----GFYCHYQPKVIYLSVVSILGILSIVVSLWDKF----SEPALRPL- 333
            |:::...||.:...:|    .:|..:.  :.:|...:..|.||.....:.|:    ..|.:|.:
Human   150 GVSVYQYGSALAHFFYSSDQAWYDRFW--LFFLPAAAFCGWLSCAGCCYAKYRYRRPYPVMRKIC 212

  Fly   334 ---RAGVFMSFGLSGVIPAIHYSIMEGWFSQMSRASLGWL-ILMGLLYILGALLYALRVPERWFP 394
               .||:.....:|.|...:....:.|...|.:     |. .|..|.:::.|..::..|||::||
Human   213 QVVPAGLAFILDISPVAHRVALCHLAGCQEQAA-----WYHTLQILFFLVSAYFFSCPVPEKYFP 272

  Fly   395 GKFDIWGQSHQIFHILV-------IAAAFVHYHGISEMAMYR 429
            |..||.|..|||||..:       :.|..:.|.|..|:.:.|
Human   273 GSCDIVGHGHQIFHAFLSICTLSQLEAILLDYQGRQEIFLQR 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdipoR	NP_651061.1	HlyIII	198..419	CDD:427098	58/240 (24%)
PAQR8	NP_588608.1	HlyIII	70..297	CDD:427098	57/233 (24%)