DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdipoR and adipor2

DIOPT Version :9

Sequence 1:	NP_001247239.1	Gene:	AdipoR / 42656	FlyBaseID:	FBgn0038984	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001020677.1	Gene:	adipor2 / 560140	ZFINID:	ZDB-GENE-041210-60	Length:	358	Species:	Danio rerio

Alignment Length:	342	Identity:	188/342 - (54%)
Similarity:	233/342 - (68%)	Gaps:	30/342 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 ILEYDDELVEEDDAGCPLPSTPEDTQLIEAEMTEVLKAGVLSDEIDLGAL--AHNAAEQAEEFVR 154
            :.|.:||..||::        .||..               |||   |.|  ||:|.|:.||||.
Zfish    31 VREEEDEEEEEEE--------EEDKS---------------SDE---GLLLQAHHAMERMEEFVH 69

  Fly   155 KVWEASWKVCHYKNLPKWLQDNDFLHRGHRPPLPSFRACFKSIFRVHTETGNIWTHLLGCIAFIG 219
            |:||..|:|..:..||.||:|||||..|||||:||||||||||||:||||||||||||||:.|:.
Zfish    70 KMWEGRWRVIPHDVLPDWLKDNDFLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGCLFFLC 134

  Fly   220 VALYFISRPSVEIQT--QEKIVFGAFFIGAIVCLGFSFAFHTLSCHSVEMGRLFSKLDYCGIALL 282
            :.:.::.||::....  |||||.|.||:|||:||.||:.|||:.|||..:.|:||||||.|||.|
Zfish   135 LGIVYMFRPNMSFVAPFQEKIVIGMFFLGAILCLSFSWLFHTVYCHSEGVSRVFSKLDYSGIAFL 199

  Fly   283 IMGSFVPWLYYGFYCHYQPKVIYLSVVSILGILSIVVSLWDKFSEPALRPLRAGVFMSFGLSGVI 347
            |||||||||||.|||..||..|||.||.||||.:|.||..|.|:.|..|.:|||||:..|||||:
Zfish   200 IMGSFVPWLYYSFYCSPQPCFIYLIVVCILGIAAITVSQCDFFATPQYRGVRAGVFVGLGLSGVV 264

  Fly   348 PAIHYSIMEGWFSQMSRASLGWLILMGLLYILGALLYALRVPERWFPGKFDIWGQSHQIFHILVI 412
            |.:|:.|.||:....:...:|||.||.:|||.||.|||.|:|||:||||.|||..|||:|||||:
Zfish   265 PTLHFMIAEGFLKATTMGQMGWLFLMAVLYITGACLYAARIPERFFPGKCDIWFHSHQLFHILVV 329

  Fly   413 AAAFVHYHGISEMAMYR 429
            |.||||:||:|.:..:|
Zfish   330 AGAFVHFHGVSNLQEFR 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdipoR	NP_001247239.1	HlyIII	198..419	CDD:397239	134/222 (60%)
adipor2	NP_001020677.1	HlyIII	113..336	CDD:308575	134/222 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	297	1.000	Domainoid score	I1428
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1958
OMA	1	1.010	-	-		QHG53658
OrthoDB	1	1.010	-	-		D1524940at2759
OrthoFinder	1	1.000	-	-		FOG0001022
OrthoInspector	1	1.000	-	-		otm25971
orthoMCL	1	0.900	-	-		OOG6_100486
Panther	1	1.100	-	-	LDO	PTHR20855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R26
SonicParanoid	1	1.000	-	-		X679
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010