DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdipoR and adipor1a

DIOPT Version :9

Sequence 1:	NP_001247239.1	Gene:	AdipoR / 42656	FlyBaseID:	FBgn0038984	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001314683.1	Gene:	adipor1a / 436740	ZFINID:	ZDB-GENE-040718-169	Length:	375	Species:	Danio rerio

Alignment Length:	368	Identity:	189/368 - (51%)
Similarity:	254/368 - (69%)	Gaps:	27/368 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 EDSLSPNDLDILEYDDELVEEDDAGCPLPSTPEDTQLIEAEMTEVLKAGVLSDE----------I 136
            |:...|.|::::|. ..|:||:.        |...:.:::|     .||.|:|:          :
Zfish    17 EECHVPADVELMEL-GPLLEENG--------PMGAKGLQSE-----GAGALADDEEEDEEVGEVL 67

  Fly   137 DLGALAHNAAEQAEEFVRKVWEASWKVCHYKNLPKWLQDNDFLHRGHRPPLPSFRACFKSIFRVH 201
            .|...||:|.|:.||||.||||..|:|..:..||:||:|||:|..|||||:|||||||.||||:|
Zfish    68 TLPLQAHHAMEKMEEFVHKVWEGRWRVIPFHVLPEWLKDNDYLLHGHRPPMPSFRACFGSIFRIH 132

  Fly   202 TETGNIWTHLLGCIAFIGVALYFISRPSVEIQT--QEKIVFGAFFIGAIVCLGFSFAFHTLSCHS 264
            ||||||||||||.|.|:.:....:.||::....  |||:|||.||:||::||.||:.|||:.|||
Zfish   133 TETGNIWTHLLGLILFLCLGTLTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHS 197

  Fly   265 VEMGRLFSKLDYCGIALLIMGSFVPWLYYGFYCHYQPKVIYLSVVSILGILSIVVSLWDKFSEPA 329
            .::.|.||||||.||||||||||||||||.|||..||::|||::|.:|||.:|:|:.||:||.|.
Zfish   198 EKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLTIVCVLGIAAIIVAQWDRFSTPR 262

  Fly   330 LRPLRAGVFMSFGLSGVIPAIHYSIMEGWFSQMSRASLGWLILMGLLYILGALLYALRVPERWFP 394
            .||.||||||..||||::|.:|::|.||:....:...:||..|||.:||.||.|||.|:|||:||
Zfish   263 HRPTRAGVFMGLGLSGIVPTMHFTIEEGFVKATTVGQMGWFYLMGAMYITGAGLYAARIPERYFP 327

  Fly   395 GKFDIWGQSHQIFHILVIAAAFVHYHGISEMAMYRV-MYSECT 436
            ||.|||..||||||:||:||||:|::|:|.:..:|. :...||
Zfish   328 GKCDIWFHSHQIFHVLVVAAAFIHFYGVSNLQEFRYGLEGGCT 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdipoR	NP_001247239.1	HlyIII	198..419	CDD:397239	133/222 (60%)
adipor1a	NP_001314683.1	HlyIII	129..352	CDD:281059	133/222 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594448
Domainoid	1	1.000	297	1.000	Domainoid score	I1428
eggNOG	1	0.900	-	-		E1_COG1272
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1958
OMA	1	1.010	-	-		QHG53658
OrthoDB	1	1.010	-	-		D1524940at2759
OrthoFinder	1	1.000	-	-		FOG0001022
OrthoInspector	1	1.000	-	-		otm25971
orthoMCL	1	0.900	-	-		OOG6_100486
Panther	1	1.100	-	-	O	PTHR20855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R26
SonicParanoid	1	1.000	-	-		X679
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.840