DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdipoR and Adipor1

DIOPT Version :9

Sequence 1:	NP_001247239.1	Gene:	AdipoR / 42656	FlyBaseID:	FBgn0038984	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_997470.2	Gene:	Adipor1 / 289036	RGDID:	1303151	Length:	375	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	188/359 - (52%)
Similarity:	250/359 - (69%)	Gaps:	7/359 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PEDSLSPNDLDILEYDDELVEEDDAGCPLPSTPEDTQLIEAEMTEVLKAGVLSDEIDLGALAHNA 145
            |..:.:.:.:::.|....|.|:.......|:..|:.|.......|..:..||:    |...||:|
  Rat    16 PSSNRAADTVELAELGPLLEEKGKRAATSPAKAEEEQACPVPQEEEEEVRVLT----LPLQAHHA 76

  Fly   146 AEQAEEFVRKVWEASWKVCHYKNLPKWLQDNDFLHRGHRPPLPSFRACFKSIFRVHTETGNIWTH 210
            .|:.||||.||||..|:|..|..||.||:|||:|..|||||:||||||||||||:||||||||||
  Rat    77 MEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTH 141

  Fly   211 LLGCIAFIGVALYFISRPSVEIQT--QEKIVFGAFFIGAIVCLGFSFAFHTLSCHSVEMGRLFSK 273
            |||.:.|:.:.:..:.||::....  |||:|||.||:||::||.||:.|||:.|||.::.|.|||
  Rat   142 LLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSK 206

  Fly   274 LDYCGIALLIMGSFVPWLYYGFYCHYQPKVIYLSVVSILGILSIVVSLWDKFSEPALRPLRAGVF 338
            |||.||||||||||||||||.|||..||::||||:|.:|||.:|:|:.||:|:.|..|..|||||
  Rat   207 LDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVF 271

  Fly   339 MSFGLSGVIPAIHYSIMEGWFSQMSRASLGWLILMGLLYILGALLYALRVPERWFPGKFDIWGQS 403
            :..|||||:|.:|::|.||:....:...:||..||.::||.||.|||.|:|||:||||||||.||
  Rat   272 LGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQS 336

  Fly   404 HQIFHILVIAAAFVHYHGISEMAMYRV-MYSECT 436
            |||||:||:||||||::|:|.:..:|. :...||
  Rat   337 HQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCT 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdipoR	NP_001247239.1	HlyIII	198..419	CDD:397239	133/222 (60%)
Adipor1	NP_997470.2	HlyIII	129..352	CDD:397239	133/222 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352507
Domainoid	1	1.000	299	1.000	Domainoid score	I1390
eggNOG	1	0.900	-	-		E1_COG1272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69199
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1900
OMA	1	1.010	-	-		QHG53658
OrthoDB	1	1.010	-	-		D1524940at2759
OrthoFinder	1	1.000	-	-		FOG0001022
OrthoInspector	1	1.000	-	-		otm44454
orthoMCL	1	0.900	-	-		OOG6_100486
Panther	1	1.100	-	-	O	PTHR20855
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X679
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770