Protein Alignment AdipoR and MMD2

DIOPT Version :10

• Sequence 1: NP_651061.1
• Gene: AdipoR / 42656
• FlyBaseID: FBgn0038984
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_001094070.1
• Gene: MMD2 / 221938
• HGNCID: 30133
• Length: 270
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 59/260 - (22%)
• Similarity: 103/260 - (39%)
• Gaps: 51/260 - (19%)

  Fly   201 HTETGNIWTHLLGCI-AFIGVA-LYFISRPSVEIQTQEKIVFGAFFIGAIVCLGFSFAFHTLS-- 261
            :....|..||....| :.:|.: |||:|....|  |....::|....|..|   .|..|||:|
Human    33 YEHAANCATHAFWIIPSILGSSNLYFLSDDDWE--TISAWIYGLGLCGLFV---VSTVFHTISWK 92

  Fly   262 -CHSVEMGRLFSKLDYCGIALLIMGSFVPWL---YYGFYCHYQPKVIYLSVVSILGILSIVVSLW 322
             .|...:.......|...|...|..|:.|||   ..|.:..:...::::    :..:.:|.|..:
Human    93 KSHLRMVEHCLHMFDRMVIYFFIAASYAPWLNLRELGPWASHMRWLVWI----MASVGTIYVFFF 153

  Fly   323 DKFSEPALRPLRAGVFMSFGLSGVIPAIHYSIME-------GWFSQMSRASLG-----W-LILMG 374
            .:.:...::.||.......| :..:|| .|.::|       |:|..:...|:.     | |:..|
Human   154 HERTGSCVQFLRGEACPKAG-TACLPA-RYKLVELLCYVVMGFFPALVILSMPNTEGIWELVTGG 216

  Fly   375 LLYILGALLYAL--RVPERWFPGKFDIWGQSHQIFHILVIAAAFVHYHGISEMAMYRVMYSECTV 437
            :.|.||.:.:..  |:|            .:|.|:|:.|...|..||:     |::|.:|...|:
Human   217 VFYCLGMVFFKSDGRIP------------FAHAIWHLFVAFGAGTHYY-----AIWRYLYLPSTL 264

  Fly   438  437
            Human   265  264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdipoR	NP_651061.1	HlyIII	198..419	CDD:427098	53/240 (22%)
MMD2	NP_001094070.1	HlyIII	34..258	CDD:470885	57/251 (23%)