DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5326 and Elovl4

DIOPT Version :9

Sequence 1:	NP_651060.1	Gene:	CG5326 / 42655	FlyBaseID:	FBgn0038983	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_683743.2	Gene:	Elovl4 / 83603	MGIID:	1933331	Length:	312	Species:	Mus musculus

Alignment Length:	271	Identity:	111/271 - (40%)
Similarity:	160/271 - (59%)	Gaps:	20/271 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVRLNETT-------TIVDRMVNFFVEHEDLRTKQWFLSNAPGPLFMILGAYLYFCLYAGPRYM 58
            ||...|:|.       ||.|:           |...|.|..:|.|...|...||.| ::.||::|
Mouse    15 MSTAFNDTVEFYRWTWTIADK-----------RVADWPLMQSPWPTISISTLYLLF-VWLGPKWM 67

  Fly    59 RDRKPFELKNTLLVYNAVQVLLSWVLFYEGYKGGWGGHYNFKCQPVTYESDPISMRMARAVWLYY 123
            :||:||:::..|::||...|||:..:|.|.:.|.:...|::.||.|.|.:|...:|:|.|:|.|:
Mouse    68 KDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNDVNEVRIAGALWWYF 132

  Fly   124 IAKITELLDTVFFVLRKKQRQISFLHLYHHTLMPVCAFIGVKYFAGGHGTLLGFINSFIHIIMYA 188
            ::|..|.||||||:||||..|:||||:|||..|....:||:|:.|||.......:|||||:|||:
Mouse   133 VSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQMNSFIHVIMYS 197

  Fly   189 YYLLSAMGPKVQKYLWWKKYITILQIVQFLIIFVHTLQIQFQPNCNFPKSIAALLTFNAGLFTYM 253
            ||.|:|.||.:|||||||:|:|:||:|||.:...|| .:....:|.|||.:...|...|..|.::
Mouse   198 YYGLTAFGPWIQKYLWWKRYLTMLQLVQFHVTIGHT-ALSLYTDCPFPKWMHWALIAYAISFIFL 261

  Fly   254 FSAFYVANYKK 264
            |..||...|.:
Mouse   262 FLNFYTRTYNE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5326	NP_651060.1	ELO	31..262	CDD:395916	101/230 (44%)
Elovl4	NP_683743.2	ELO	41..277	CDD:279492	102/234 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..312		111/271 (41%)
		Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03204, ECO:0000269\|PubMed:24569140	308..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820