DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5326 and ELOVL3

DIOPT Version :9

Sequence 1:	NP_651060.1	Gene:	CG5326 / 42655	FlyBaseID:	FBgn0038983	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_689523.1	Gene:	ELOVL3 / 83401	HGNCID:	18047	Length:	270	Species:	Homo sapiens

Alignment Length:	260	Identity:	75/260 - (28%)
Similarity:	111/260 - (42%)	Gaps:	69/260 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FFVEHEDLRTKQWFLSNAPGPLFMILGAYLYFCLYA-GPRYMRDRKPFELKNTLLVYN------- 74
            ||.|:       |..|      |.|  |.:|..|.| |..||::||.|.|:..|::::
Human    29 FFEEY-------WATS------FPI--ALIYLVLIAVGQNYMKERKGFNLQGPLILWSFCLAIFS 78

  Fly    75 ---AVQV--LLSWVLFYEGYKGGWGGHYNFKCQPVTYESDPISMRMARAVWLYYIAKITELLDTV 134
               ||::  ::..||...|.|           |.|.:.:...:..:....|::.::|:.||.||.
Human    79 ILGAVRMWGIMGTVLLTGGLK-----------QTVCFINFIDNSTVKFWSWVFLLSKVIELGDTA 132

  Fly   135 FFVLRKKQRQISFLHLYHHTLMPVCAFIGV--KYFAGGHGTLLGFINSFIHIIMYAYYLLSAMGP 197
            |.:|||  |.:.|:|.|||:.:.|....|.  |..|||....:.|   .:|.|||.||.|.|...
Human   133 FIILRK--RPLIFIHWYHHSTVLVYTSFGYKNKVPAGGWFVTMNF---GVHAIMYTYYTLKAANV 192

  Fly   198 KVQKYLWWKKYITILQIVQFLIIFVHTLQIQFQPNCNFPKSIAALLTF----NAGLFTYMFSAFY 258
            |..|.|  ...||.|||:|.                 |..:|.::||:    :.|..|.|...|:
Human   193 KPPKML--PMLITSLQILQM-----------------FVGAIVSILTYIWRQDQGCHTTMEHLFW 238

Fly 259 258
Human 239 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5326	NP_651060.1	ELO	31..262	CDD:395916	71/247 (29%)
ELOVL3	NP_689523.1	ELO	29..266	CDD:307345	75/260 (29%)
ELOVL3	NP_689523.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03203	266..270
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820