DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5326 and ELOVL7

DIOPT Version :10

Sequence 1:NP_651060.1 Gene:CG5326 / 42655 FlyBaseID:FBgn0038983 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_079206.2 Gene:ELOVL7 / 79993 HGNCID:26292 Length:281 Species:Homo sapiens


Alignment Length:259 Identity:115/259 - (44%)
Similarity:165/259 - (63%) Gaps:6/259 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 IVDRMVNFF---VEHEDLRTKQWFLSNAPGPLFMILGAYLYFCLYAGPRYMRDRKPFELKNTLLV 72
            :..|.|:.:   ::..|.|.:.|.|.::|.|..::||.|:||....||:.|.:|||||||..::.
Human     6 LTSRTVHLYDNWIKDADPRVEDWLLMSSPLPQTILLGFYVYFVTSLGPKLMENRKPFELKKAMIT 70

  Fly    73 YNAVQVLLSWVLFYEGYKGGWGGHYNFKCQPVTYESDPISMRMARAVWLYYIAKITELLDTVFFV 137
            ||...||.|..:.||....|||..|:|:|..|.|...|.::||||..||||.:|..|||||:|||
Human    71 YNFFIVLFSVYMCYEFVMSGWGIGYSFRCDIVDYSRSPTALRMARTCWLYYFSKFIELLDTIFFV 135

  Fly   138 LRKKQRQISFLHLYHHTLMPVCAFIGVKYFAGGHGTLLGFINSFIHIIMYAYYLLSAMGPKVQKY 202
            ||||..|::|||::|||:||...:.|||:.|||.||....:|:.:|::||:||.|||:||..|||
Human   136 LRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHALLNTAVHVVMYSYYGLSALGPAYQKY 200

  Fly   203 LWWKKYITILQIVQFLIIFVHTLQIQFQPNC--NFPKSIAALLTFNAGLFTYMFSAFYVANYKK 264
            ||||||:|.||:|||:|:.:|..|..|..:|  .||.....:::::. :|..:|..|:...|.|
Human   201 LWWKKYLTSLQLVQFVIVAIHISQFFFMEDCKYQFPVFACIIMSYSF-MFLLLFLHFWYRAYTK 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5326NP_651060.1 ELO 30..262 CDD:460083 109/233 (47%)
ELOVL7NP_079206.2 ELO 29..269 CDD:460083 110/236 (47%)
HxxHH motif. /evidence=ECO:0000305|PubMed:34117479 147..151 1/3 (33%)
Di-lysine motif. /evidence=ECO:0000255|HAMAP-Rule:MF_03207 277..281
Blue background indicates that the domain is not in the aligned region.

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