DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5326 and ELOVL1

DIOPT Version :9

Sequence 1:	NP_651060.1	Gene:	CG5326 / 42655	FlyBaseID:	FBgn0038983	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens

Alignment Length:	257	Identity:	106/257 - (41%)
Similarity:	158/257 - (61%)	Gaps:	4/257 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VDRMVNFFVE---HEDLRTKQWFLSNAPGPLFMILGAYLYFCLYAGPRYMRDRKPFELKNTLLVY 73
            ::.:||.:.|   |.|.|.:.:.|..:|..:..||..|:||.|..|||.|.:||||:|:..::||
Human     1 MEAVVNLYQEVMKHADPRIQGYPLMGSPLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVY 65

  Fly    74 NAVQVLLSWVLFYEGYKGGWGGHYNFKCQPVTYESDPISMRMARAVWLYYIAKITELLDTVFFVL 138
            |...|.||..:.||....||...|.::|.||.|.:.|.::||.|..||:..:|..||:|||.|:|
Human    66 NFSLVALSLYIVYEFLMSGWLSTYTWRCDPVDYSNSPEALRMVRVAWLFLFSKFIELMDTVIFIL 130

  Fly   139 RKKQRQISFLHLYHHTLMPVCAFIGVKYFAGGHGTLLGFINSFIHIIMYAYYLLSAMGPKVQKYL 203
            |||..|::|||::||:::|...:.|||...||.|:....|||.:|:|||.||.|||.||..|.||
Human   131 RKKDGQVTFLHVFHHSVLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYL 195

  Fly   204 WWKKYITILQIVQFLIIFVHTLQIQFQPNCNFPKSIAALLTFNAG-LFTYMFSAFYVANYKK 264
            ||||::|.:|::||:::.:|..|..|..:||:...:...|.:..| :|..:||.|:..:|.|
Human   196 WWKKHMTAIQLIQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSYTK 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5326	NP_651060.1	ELO	31..262	CDD:395916	98/231 (42%)
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	100/235 (43%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920