DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5326 and Elovl2

DIOPT Version :9

Sequence 1:	NP_651060.1	Gene:	CG5326 / 42655	FlyBaseID:	FBgn0038983	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_062296.1	Gene:	Elovl2 / 54326	MGIID:	1858960	Length:	292	Species:	Mus musculus

Alignment Length:	273	Identity:	103/273 - (37%)
Similarity:	150/273 - (54%)	Gaps:	23/273 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DRMVNFFVEH----EDLRTKQWFLSNAPGPLFMILGAYLYFCLYAGPRYMRDRKPFELKNTLLVY 73
            |..||.|:::    .|.|.:.|||.::..|.|::...|| ..::.|.:||::|....|:..|.:|
Mouse     8 DNEVNAFLDNMFGPRDSRVRGWFLLDSYLPTFILTITYL-LSIWLGNKYMKNRPALSLRGILTLY 71

  Fly    74 NAVQVLLSWVLFYEGYKGGWGGHYNFKCQPV--TYESDPISMRMARAVWLYYIAKITELLDTVFF 136
            |....|||..:..|.....|.|.||.:||.:  ..|.|   :|:|:.:|.||.:|:.|.|||:||
Mouse    72 NLAITLLSAYMLVELILSSWEGGYNLQCQNLDSAGEGD---VRVAKVLWWYYFSKLVEFLDTIFF 133

  Fly   137 VLRKKQRQISFLHLYHHTLMPVCAFIGVKYFAGGHGTLLGFINSFIHIIMYAYYLLSAMGPKVQK 201
            |||||..||:|||:|||..|....:..:.:...|.......:||||||:||:||.||.. |.:.|
Mouse   134 VLRKKTNQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVF-PSMHK 197

  Fly   202 YLWWKKYITILQIVQFLIIFVHTLQIQFQPNCNFPKSIAALLTFNAGLFT--YMFSAFYVANYKK 264
            |||||||:|..|:|||::...|||....:| |.||  ...|:..::.:.|  .:|..||:..|:|
Mouse   198 YLWWKKYLTQAQLVQFVLTITHTLSAVVKP-CGFP--FGCLIFQSSYMMTLVILFLNFYIQTYRK 259

  Fly   265 EAAAQAKLAAKKE 277
            :       ..|||
Mouse   260 K-------PVKKE 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5326	NP_651060.1	ELO	31..262	CDD:395916	91/234 (39%)
Elovl2	NP_062296.1	ELO	30..264	CDD:307345	93/248 (38%)
Elovl2	NP_062296.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03202	289..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820