DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33093 and CG5346

DIOPT Version :9

Sequence 1:	NP_788715.2	Gene:	CG33093 / 42654	FlyBaseID:	FBgn0053093	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_651058.1	Gene:	CG5346 / 42653	FlyBaseID:	FBgn0038981	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	394	Identity:	174/394 - (44%)
Similarity:	229/394 - (58%)	Gaps:	84/394 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ETLLLQNAVPIIDL----------ENTIEDVATNLREALSEKGYALLINHGISNEKIKKAWKYFD 60
            :|||.::.||||||          ::.:..|...|::||||||.|||:|||||:||:|.||.:.|
  Fly    12 DTLLSRSVVPIIDLAHCGIEEVPVKSVVNRVGHQLKKALSEKGMALLVNHGISDEKLKTAWDHLD 76

  Fly    61 GFVDLTDEVKLAFERSKAPDGENHGYVSPG-MERFDGRTPELRHAYNICKLQDKFLPEQQLPGFS 124
            .||:|..:::..:.|:   ||:.|||||.| .:||||::||||||:||..|..:.|||:.||||:
  Fly    77 DFVNLPPDIRQHYIRA---DGDKHGYVSRGQQQRFDGKSPELRHAFNISTLNAQNLPEEPLPGFA 138

  Fly   125 RHINSLVDDFNELGRFILKALAISLDAPPSFFTDKHSFMLSDDRFNLTTLRMLFYPPVEDQDHGR 189
            .||::|..||..|..|||:|||:|||.|.:||.:|||.|||.|..|:::||||:|||:.|.:.|:
  Fly   139 DHISTLATDFKALASFILQALAVSLDIPHTFFLEKHSHMLSGDHDNMSSLRMLYYPPIVDDEPGQ 203

  Fly   190 ----------------------------------------------------SFIRCGAHADYCT 202
                                                                :.|:|..|.||.|
  Fly   204 NDVIKGRCQYSYQRCLSNQPDFRPEHNPRDEDDLNEVDGPNGQLFEHKLGNGAVIQCPPHVDYGT 268

  Fly   203 FTLLAQDSEGGLEVKLRGSDKWERVGHLPGALFINCGETMAIWTDQFYHALQHRVVIPDQVDIRH 267
            ||||:|||||||||:|.||:||.|||||||::.:||||.:.|||...|.||||||:||:|..||.
  Fly   269 FTLLSQDSEGGLEVRLPGSEKWNRVGHLPGSILVNCGEILNIWTQGRYPALQHRVIIPEQETIRA 333

  Fly   268 RGRHSIAYFCHPDNSALINPKDL--------NITTKQ------TTSDVIQNAYDITMALAKGAFA 318
            |||||||:||||||...|:|.||        ....||      ...:.:.|||.    |.:..|.
  Fly   334 RGRHSIAFFCHPDNITTISPTDLPNPDAVQDKACLKQRKKSFKAAKERVYNAYQ----LIQKKFR 394

  Fly   319 HHYS 322
            ..||
  Fly   395 DTYS 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33093	NP_788715.2	PcbC	13..287	CDD:226022	159/336 (47%)
		DIOX_N	14..107	CDD:290926	50/103 (49%)
		2OG-FeII_Oxy	179..279	CDD:281202	64/151 (42%)
CG5346	NP_651058.1	PcbC	16..367	CDD:226022	162/353 (46%)
		DIOX_N	20..131	CDD:290926	54/113 (48%)
		2OG-FeII_Oxy	<260..345	CDD:281202	58/84 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469694
Domainoid	1	1.000	64	1.000	Domainoid score	I3647
eggNOG	1	0.900	-	-		E1_COG3491
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I2188
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D440238at33208
OrthoFinder	1	1.000	-	-		FOG0012092
OrthoInspector	1	1.000	-	-		otm25841
orthoMCL	1	0.900	-	-		OOG6_100398
Panther	1	1.100	-	-	P	PTHR10209
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X166
	10	9.890