DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta1R and LOC563567

DIOPT Version :9

Sequence 1:	NP_001262843.1	Gene:	Octbeta1R / 42652	FlyBaseID:	FBgn0038980	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_005158584.1	Gene:	LOC563567 / 563567	-ID:	-	Length:	447	Species:	Danio rerio

Alignment Length:	341	Identity:	126/341 - (36%)
Similarity:	194/341 - (56%)	Gaps:	18/341 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 SEGSTDDADGSSHLALVFVKCFIIGFIILAAILGNMLVIVSVMRHRKLRI-ITNYFVVSLAVADM 154
            :.|:.:..||....::..:..|::..:|::.:|||.||..:|::.|.||. :||:||:||||:|:
Zfish    18 AHGAQEREDGDGQNSVRALLGFVLFLLIVSTLLGNTLVCAAVVKFRHLRSKVTNFFVISLAVSDL 82

  Fly   155 LVALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFSTASIMHLCCISVDRYYAIVQPLDYPLIM 219
            .||:..|.:.|...::|.|:||. .|.:|.:||:..|||||::||.||||||:||..|..|...|
Zfish    83 FVAVLVMPWEAISAVAGTWLFGR-FCGIWIAFDIMCSTASILNLCIISVDRYWAIASPFRYERKM 146

  Fly   220 TQRRVFIMLLMVWLSPALLSFLPICSGWYTTTENYKYLKSN----PHICEFKVNKAYAIVSSSMS 280
            |.|..|:|:.:.|....|:||:|:...|:...::.:....|    ...|:..:|:.|||.||.:|
Zfish   147 THRVAFMMIGVAWTLSILISFIPVQLNWHMADDDEEGAGGNGTDYSDNCKANLNRTYAISSSLIS 211

  Fly   281 FWIPGIVMLSMYYRIYQEADRQERLVYRSKVAALLLEKHLQISQIPKPRPSIQVEQSTISTMRRE 345
            |:||.|:|::.|.||::.|..|.|.:...:.|....:.|.|.:....       |.|..:|.::|
Zfish   212 FYIPVIIMIATYTRIFRIAQTQIRRISSLERAVEHAQNHHQSNDCSN-------ENSLKTTFKKE 269

  Fly   346 RKAARTLGIIMSAFLICWLPFFLWYIVSSLCDSCITPRLLVGILFWIGYFNSALNPIIYAYFNRD 410
            .|..:||.|||..|:.||||||:...:...| .|::..... |..|.|:.||:|||:||| ||.|
Zfish   270 TKVLKTLSIIMGVFVFCWLPFFVLNCMVPFC-QCVSDTTFT-IFVWFGWANSSLNPVIYA-FNAD 331

  Fly   411 FRAAFKKTL--KSLFP 424
            ||.||...|  ..:||
Zfish   332 FRKAFSSILGCNKIFP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	54/119 (45%)
Octbeta1R	NP_001262843.1	7tm_1	124..404	CDD:278431	107/284 (38%)
LOC563567	XP_005158584.1	7tmA_D1-like_dopamine_R	35..336	CDD:320185	118/311 (38%)
		TM helix 1	36..62	CDD:320185	8/25 (32%)
		TM helix 2	70..97	CDD:320185	13/26 (50%)
		TM helix 3	107..137	CDD:320185	18/29 (62%)
		TM helix 4	149..169	CDD:320185	7/19 (37%)
		TM helix 5	200..230	CDD:320185	15/29 (52%)
		TM helix 6	267..297	CDD:320185	14/29 (48%)
		TM helix 7	305..330	CDD:320185	12/26 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010