DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Octbeta1R and Dop1R1

DIOPT Version :9

Sequence 1:	NP_001262843.1	Gene:	Octbeta1R / 42652	FlyBaseID:	FBgn0038980	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001262563.1	Gene:	Dop1R1 / 41726	FlyBaseID:	FBgn0011582	Length:	560	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	161/529 - (30%)
Similarity:	247/529 - (46%)	Gaps:	117/529 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AMSATTTRTILEGSISSFGG---------GTNEPL--ASKIPVLEESASHARY-------LKFIA 55
            ::|::|| .|...|.::.||         .||..|  |..:|:   ..:.|:.       ::.:.
  Fly    29 SISSSTT-IINTSSATTIGGNHTSGSTGFSTNSTLLDADHLPL---QLTTAKVDLDIEIDIQLLT 89

  Fly    56 DGLIDEGLGSAVGSGSSIAVSVEDVVAGQAQDIQASEGSTDDADGSSHLALVFVKCFIIGFIILA 120
            :|.....|.|.....|....|..|.:.|            ::.:..|.:::|.|..| :..:|..
  Fly    90 NGYDGTTLTSFYNESSWTNASEMDTIVG------------EEPEPLSLVSIVVVGIF-LSVLIFL 141

  Fly   121 AILGNMLVIVSVMRHRKLRIITNYFVVSLAVADMLVALCAMTFNASVMISGKWMFGSVMCDMWNS 185
            ::.||:||.:::...|.||.|.|.|:.|||:||:.||...|||.....:.|.|:||:..||.|.:
  Fly   142 SVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVA 206

  Fly   186 FDVYFSTASIMHLCCISVDRYYAIVQPLDYPLIMTQRRVFIMLLMVWLSPALLSFLPICSGWYTT 250
            |||..|||||::||.||:|||..|..||.|...:|:|...|.:..:||..|.:||:||..|.:..
  Fly   207 FDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRP 271

  Fly   251 TE-------NYKYLKSNPHICEFKVNKAYAIVSSSMSFWIPGIVMLSMYYRIYQEADRQERLVYR 308
            .:       ..||     ..|...:...||:|||.:||:.|.:||:.:|.|:|..|
  Fly   272 DQPLIFEDNGKKY-----PTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYA--------- 322

  Fly   309 SKVAALLLEKHLQ-ISQIPKP-------------RPSIQVEQSTISTMR--------RERKAART 351
                    :||:: |..:.:|             ||..|.::..:..:.        .:.|||.|
  Fly   323 --------QKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVT 379

  Fly   352 LGIIMSAFLICWLPFFLWYIVSSLCDSCITPRLLVGILFWIGYFNSALNPIIYAYFNRDFRAAFK 416
            :|:||..|||||:|||...|.::.|.:||..:.. .||.|:||.|||.|||||:.||::||.|||
  Fly   380 VGVIMGVFLICWVPFFCVNITAAFCKTCIGGQTF-KILTWLGYSNSAFNPIIYSIFNKEFRDAFK 443

  Fly   417 KTLKSLFPYAFYFCRRGRG----RDDDRDLEFGGPSRRGTNGAQR------TGSGSAEMAN---- 467
            :.|....|:.   |.:..|    |:.||.:         |:.|.:      :|..|||:..
  Fly   444 RILTMRNPWC---CAQDVGNIHPRNSDRFI---------TDYAAKNVVVMNSGRSSAELEQVSAI 496

  Fly   468 ----CVNST 472
                |:|.|
  Fly   497 XPKCCLNLT 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	51/118 (43%)
Octbeta1R	NP_001262843.1	7tm_1	124..404	CDD:278431	111/308 (36%)
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	58/132 (44%)
Dop1R1	NP_001262563.1	7tm_1	145..431	CDD:278431	111/308 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460619
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840