Protein Alignment Octbeta1R and HTR4

DIOPT Version :9

• Sequence 1: NP_001262843.1
• Gene: Octbeta1R / 42652
• FlyBaseID: FBgn0038980
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001035263.1
• Gene: HTR4 / 3360
• HGNCID: 5299
• Length: 428
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 149/397 - (37%)
• Similarity: 208/397 - (52%)
• Gaps: 59/397 - (14%)

  Fly    94 STDDADGSSHLALVFVKCFIIGFIILAAILGNMLVIVSVMRHRKLR-IITNYFVVSLAVADMLVA 157
            |:::..||....::..   .:..:||.|||||:||:|:|...|:|| |.||||:||||.||:||:
Human     9 SSEEGFGSVEKVVLLT---FLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVS 70

  Fly   158 LCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFSTASIMHLCCISVDRYYAI-VQPLDYPLIMTQ 221
            :..|.|.|..::...|::|.|.|.:..|.||..:||||.||||||:|||||| .|||.|...||.
Human    71 VLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTP 135

  Fly   222 RRVFIMLLMVWLSPALLSFLPICSGW-----YTTTENYKY-LKSNPHICEFKVNKAYAIVSSSMS 280
            .|:.:||...|:.|..:|||||..||     ....|..|: ..||...|.|.|||.|||..|.::
Human   136 LRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200

  Fly   281 FWIPGIVMLSMYYRIY---QEADRQERLVYRSKVAALLLEKHLQISQIPKPRPSIQVEQSTISTM 342
            |:||.::|:..|||||   :|...|.:::.|:..::             :.||. ..:|.:...|
Human   201 FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASS-------------ESRPQ-SADQHSTHRM 251

  Fly   343 RRERKAARTLGIIMSAFLICWLPFFLWYIVSSLCDSCITPRLLVGILFWIGYFNSALNPIIYAYF 407
            |.|.|||:||.|||..|.:||.|||:..||....|..:..::....| |:||.||.|||.:||:.
Human   252 RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL-WLGYINSGLNPFLYAFL 315

  Fly   408 NRDFRAAFKKTLKSLFPYAFYFCRRGRGRDDDRDLEFGGPSRRGTNGAQRTGSGSAEMANCVNST 472
            |:.||.||...|         .|      ||:|   :..||..|            :...|..:|
Human   316 NKSFRRAFLIIL---------CC------DDER---YRRPSILG------------QTVPCSTTT 350

  Fly   473 ASSEIHM 479
            .:...|:
Human   351 INGSTHV 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	62/120 (52%)
		7tm_1	124..404	CDD:278431	123/290 (42%)
HTR4	NP_001035263.1	7tm_1	36..312	CDD:278431	123/290 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20243
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D328277at33208
OrthoFinder	1	1.000	-	-		FOG0005484
OrthoInspector	1	1.000	-	-		otm40768
orthoMCL	1	0.900	-	-		OOG6_107218
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4996
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.850