DRSC/TRiP Functional Genomics Resources

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Protein Alignment Octbeta1R and Htr4

DIOPT Version :9

Sequence 1:NP_001262843.1 Gene:Octbeta1R / 42652 FlyBaseID:FBgn0038980 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_036985.2 Gene:Htr4 / 25324 RGDID:2850 Length:388 Species:Rattus norvegicus


Alignment Length:334 Identity:140/334 - (41%)
Similarity:191/334 - (57%) Gaps:30/334 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 DADGSSHLALVFVKCFII----GFIILAAILGNMLVIVSVMRHRKLR-IITNYFVVSLAVADMLV 156
            ||:.||:.....|:..::    ..:||.|||||:||:|:|.|.|:|| |.||||:||||.||:||
  Rat     5 DANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLV 69

  Fly   157 ALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFSTASIMHLCCISVDRYYAI-VQPLDYPLIMT 220
            ::..|.|.|..::...|.:|.:.|.:..|.||..:||||.||||||:|||||| .|||.|...||
  Rat    70 SVLVMPFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

  Fly   221 QRRVFIMLLMVWLSPALLSFLPICSGW-----YTTTENYKY-LKSNPHICEFKVNKAYAIVSSSM 279
            ..|:.:||...|:.|..:|||||..||     ....|..|: ..||...|.|.|||.|||..|.:
  Rat   135 PLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVV 199

  Fly   280 SFWIPGIVMLSMYYRIY---QEADRQERLVYRSKVAALLLEKHLQISQIPKPRPSIQVEQSTIST 341
            :|:||.::|:..|||||   :|..:|.:::.|:...:             :.||....:.|| ..
  Rat   200 AFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATS-------------ESRPQTADQHST-HR 250

  Fly   342 MRRERKAARTLGIIMSAFLICWLPFFLWYIVSSLCDSCITPRLLVGILFWIGYFNSALNPIIYAY 406
            ||.|.|||:||.:||..|..||.|||:..||....|..:..::....| |:||.||.|||.:||:
  Rat   251 MRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFL-WLGYINSGLNPFLYAF 314

  Fly   407 FNRDFRAAF 415
            .|:.||.||
  Rat   315 LNKSFRRAF 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Octbeta1RNP_001262843.1 7tm_4 112..>231 CDD:304433 62/124 (50%)
7tm_1 124..404 CDD:278431 123/290 (42%)
Htr4NP_036985.2 7tmA_5-HT4 20..323 CDD:320184 133/317 (42%)
TM helix 1 22..46 CDD:320184 11/23 (48%)
TM helix 2 56..78 CDD:320184 13/21 (62%)
TM helix 3 94..116 CDD:320184 12/21 (57%)
TM helix 4 140..156 CDD:320184 6/15 (40%)
TM helix 5 190..213 CDD:320184 9/22 (41%)
TM helix 6 258..280 CDD:320184 11/21 (52%)
TM helix 7 291..316 CDD:320184 11/25 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H20243
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D328277at33208
OrthoFinder 1 1.000 - - FOG0005484
OrthoInspector 1 1.000 - - otm44908
orthoMCL 1 0.900 - - OOG6_107218
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.820

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