DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta1R and taar19b

DIOPT Version :9

Sequence 1:	NP_001262843.1	Gene:	Octbeta1R / 42652	FlyBaseID:	FBgn0038980	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_021335134.1	Gene:	taar19b / 100333348	ZFINID:	ZDB-GENE-091116-74	Length:	334	Species:	Danio rerio

Alignment Length:	359	Identity:	98/359 - (27%)
Similarity:	164/359 - (45%)	Gaps:	63/359 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 VAGQAQDIQASEGSTDDADGS----SHLALVFVKCFIIGFIILAAILGNMLVIVSVMRHRKLRII 141
            :|.:.:| |.::....|.:.|    .|....::....:.|:....:..|:|||:|:...:||...
Zfish     1 MAYETED-QETQYCFPDINSSCVKEQHSTNGYIIYLFVSFLSAWTVFLNLLVIISISHFKKLHTP 64

  Fly   142 TNYFVVSLAVADMLVALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFSTASIMHLCCISVDRY 206
            ||..|:||||||:|:.|..|...|..:|...|.||...|...........:||:.:|..|:||||
Zfish    65 TNMIVLSLAVADLLIGLIVMPVEAVKLIETCWYFGDTFCGFTLILIGVIPSASLGNLVLIAVDRY 129

  Fly   207 YAIVQPLDYPLIMTQRRVFIMLLMVWLSPALLSFLPICSGWYTTTENYKYLKSNPHICEFKVNKA 271
            .|:..||.||..:|...:.:.:.:.|:         ..|.:.||...|.......|    :.::.
Zfish   130 AAVCHPLLYPQKITMANMLMSICLSWV---------YYSTYITTLVIYNRYFDTSH----RTDEC 181

  Fly   272 YAIVSSSMSF-WI----------PGIVMLSMYYRIYQEADRQERLVYRSKVAALLLEKHLQISQI 325
            |......||| ||          |.::::::|.||:....:|.::                |:.:
Zfish   182 YGQCLVMMSFSWILTDLFVCFVFPCVLIITLYLRIFYVVHQQVKV----------------INSL 230

  Fly   326 PKPRPSIQVEQSTISTMRR--ERKAARTLGIIMSAFLICWLPFFLWYIVSSLCDSCITPRLLVGI 388
            .|....:     |..:::|  |.|||.|||||:|.:|:||:|::       :|...:....::.:
Zfish   231 MKGGKCV-----TEGSVKRKSESKAALTLGIIVSVYLLCWIPYY-------ICTLTVNSSTVLSV 283

  Fly   389 LFWIGYFNSALNPIIYAYFNRDFRAAFKKTLKSL 422
            |.|:.|.||.|||::||.    |...||||:|.:
Zfish   284 LTWVLYANSGLNPLVYAL----FYPWFKKTVKHI 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	40/118 (34%)
Octbeta1R	NP_001262843.1	7tm_1	124..404	CDD:278431	83/292 (28%)
taar19b	XP_021335134.1	7tmA_TAARs	32..310	CDD:320183	90/322 (28%)
		TM helix 1	32..58	CDD:320183	6/25 (24%)
		TM helix 2	65..91	CDD:320183	13/25 (52%)
		TM helix 3	103..133	CDD:320183	10/29 (34%)
		TM helix 4	145..168	CDD:320183	4/31 (13%)
		TM helix 5	190..219	CDD:320183	8/28 (29%)
		TM helix 6	245..275	CDD:320183	15/36 (42%)
		TM helix 7	278..303	CDD:320183	10/28 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910