DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta1R and taar20o

DIOPT Version :9

Sequence 1:	NP_001262843.1	Gene:	Octbeta1R / 42652	FlyBaseID:	FBgn0038980	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_017213636.2	Gene:	taar20o / 100002324	ZFINID:	ZDB-GENE-060414-4	Length:	350	Species:	Danio rerio

Alignment Length:	361	Identity:	101/361 - (27%)
Similarity:	176/361 - (48%)	Gaps:	45/361 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 GSGSSIAVSVEDVVAGQAQDIQASEGSTDDADGS----SHLALVFVKCFIIGFIILA-AILGNML 127
            |..|......:.::|.:.:| |.::....|.:.|    .|....::..::...::.| .:..|:|
Zfish     6 GEQSKPLTDGDSLMAYETED-QETQYCFPDINSSCVKEKHSRYGYITTYLFVSLLSAWTVFLNLL 69

  Fly   128 VIVSVMRHRKLRIITNYFVVSLAVADMLVALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFST 192
            ||:|:...:||...||..::||||.|:||.| .|...|..:|...|.||...|.::..|.....:
Zfish    70 VIISISHFKKLHTPTNMIILSLAVTDLLVGL-VMPVEAIRLIETCWYFGDTFCGLYIFFVSLLLS 133

  Fly   193 ASIMHLCCISVDRYYAIVQPLDYPLIMTQRRVFIMLLMVWLS-PALLSFLPICSGWYTTTENYKY 256
            ||:.:|..|:||||.|:..||.||..:|..:..:.:.:.|.. .|.:..|.|.:.::.|:.....
Zfish   134 ASLGNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWAGLTAYIITLVINNSYFDTSHRTDV 198

  Fly   257 LKSNPHICEFKVNKAYAIVSSSMSFWIPGIVMLSMYYRIYQEADRQERLVYRSKVAALLLEKHLQ 321
            ....   |.:.::.::.:....|||..|.|:::::|.||:....:|.::
Zfish   199 CYGQ---CLYMISYSWILTELFMSFIFPCILIITLYLRIFYVVHQQVKV---------------- 244

  Fly   322 ISQIPKPRPSIQVEQSTISTMRR--ERKAARTLGIIMSAFLICWLPFFLWYIVSSLCDSCITPRL 384
            |:.:.|....:     |..:::|  |.|||.|||||:|.:|:||:|:|::    ||..:..|  .
Zfish   245 INSLMKGGKCV-----TEGSVKRKSESKAALTLGIIVSVYLLCWIPYFIY----SLTVNAST--T 298

  Fly   385 LVGILFWIGYFNSALNPIIYAYFNRDFRAAFKKTLK 420
            :.|:||.: :.||.|||::||.    |...||||.|
Zfish   299 INGLLFAV-FANSGLNPLVYAL----FYPWFKKTAK 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	40/119 (34%)
Octbeta1R	NP_001262843.1	7tm_1	124..404	CDD:278431	84/282 (30%)
taar20o	XP_017213636.2	7tmA_TAARs	50..327	CDD:320183	90/312 (29%)
		TM helix 1	51..77	CDD:320183	6/25 (24%)
		TM helix 2	84..109	CDD:320183	12/25 (48%)
		TM helix 3	121..151	CDD:320183	11/29 (38%)
		TM helix 4	163..186	CDD:320183	3/22 (14%)
		TM helix 5	208..237	CDD:320183	8/28 (29%)
		TM helix 6	263..293	CDD:320183	17/33 (52%)
		TM helix 7	296..321	CDD:320183	11/31 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910