Protein Alignment tHMG2 and SOX8

DIOPT Version :10

• Sequence 1: NP_001163689.1
• Gene: tHMG2 / 42651
• FlyBaseID: FBgn0038979
• Length: 134
• Species: Drosophila melanogaster
• Sequence 2: NP_055402.2
• Gene: SOX8 / 30812
• HGNCID: 11203
• Length: 446
• Species: Homo sapiens
• Alignment Length: 68
• Identity: 21/68 - (30%)
• Similarity: 40/68 - (58%)
• Gaps: 3/68 - (4%)

  Fly     7 ARP--KKPMSAFMLWMNSTGRKNIRAEHPDFSVQEVSVKGGEMWRAMADEHKIVWQESASKAMAE 69
            |:|  |:||:|||:|..:..|| :..::|.....|:|...|::||.:::..|..:.|.|.:...:
Human    98 AKPHVKRPMNAFMVWAQAARRK-LADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQ 161

  Fly    70 YKE 72
            :|:
Human   162 HKK 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tHMG2	NP_001163689.1	HMG-box_SSRP1-like	11..78	CDD:438810	18/62 (29%)
SOX8	NP_055402.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58
		Sox_N	18..89	CDD:463586
		Dimerization (DIM). /evidence=ECO:0000303|PubMed:31194875	58..100		1/1 (100%)
		HMG-box_SoxE	101..175	CDD:438840	19/65 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..259		2/10 (20%)
		Transactivation domain (TAM). /evidence=ECO:0000303|PubMed:31194875	224..298
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..378
		Transactivation domain (TAC). /evidence=ECO:0000303|PubMed:31194875	335..446
		9aaTAD. /evidence=ECO:0000269|PubMed:34342803	400..408
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..446