DRSC/TRiP Functional Genomics Resources

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Protein Alignment tHMG2 and HMGB4

DIOPT Version :9

Sequence 1:NP_001163689.1 Gene:tHMG2 / 42651 FlyBaseID:FBgn0038979 Length:134 Species:Drosophila melanogaster
Sequence 2:NP_001366230.1 Gene:HMGB4 / 127540 HGNCID:24954 Length:186 Species:Homo sapiens


Alignment Length:98 Identity:27/98 - (27%)
Similarity:51/98 - (52%) Gaps:15/98 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MMSDYGAR----------PKKPMSAFMLWMNSTGRKNIRAEHPDFSVQEVSVKGGEMWRAMADEH 55
            ||:..|.|          |::|.|:|:|:... ....::.|:|::||.:|:...|:||....|..
Human    75 MMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQD-HYAQLKRENPNWSVVQVAKATGKMWSTATDLE 138

  Fly    56 KIVWQESASKAMAEYKEKLEKW----NAFKEHQ 84
            |..:::..:...|:|.|:||.:    ||.|:::
Human   139 KHPYEQRVALLRAKYFEELELYRKQCNARKKYR 171

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tHMG2NP_001163689.1 HMGB-UBF_HMG-box 9..75 CDD:238686 18/65 (28%)
HMGB4NP_001366230.1 HMG-box 8..78 CDD:412149 2/2 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 77..98 4/20 (20%)
HMG-box 93..158 CDD:238037 18/65 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1641977at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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