DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tHMG1 and Tox4

DIOPT Version :9

Sequence 1:	NP_651055.1	Gene:	tHMG1 / 42650	FlyBaseID:	FBgn0038978	Length:	126	Species:	Drosophila melanogaster
Sequence 2:	NP_075923.2	Gene:	Tox4 / 268741	MGIID:	1915389	Length:	619	Species:	Mus musculus

Alignment Length:	106	Identity:	28/106 - (26%)
Similarity:	49/106 - (46%)	Gaps:	14/106 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PKKPMSAFMLWMNSTGRKHIKAEHPDFSVQEVSVKGGEMWRAMADEDKIVWQESATTAMAEYKEK 72
            |:||:||:.|:...| :..||.::|:.:..|||.....||.::.:|.|.|::.....|..||.:.
Mouse   223 PQKPVSAYALFFRDT-QAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKA 286

  Fly    73 LKQWNFPKEHRFSDTQCICSSNTNQCPTLFVYDTMDDSMTP 113
            |..:.       .:.:|..:..|.:      .|.:..|.||
Mouse   287 LAAYK-------DNQECQATVETVE------LDPVPQSQTP 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tHMG1	NP_651055.1	HMGB-UBF_HMG-box	8..74	CDD:238686	21/65 (32%)
tHMG1	NP_651055.1	Herpes_U55	<55..>116	CDD:253772	12/59 (20%)
Tox4	NP_075923.2	NHP6B	140..>306	CDD:227935	24/96 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..227		2/3 (67%)
		Nuclear localization signal. /evidence=ECO:0000255	213..218
		HMG-box	223..288	CDD:238037	21/65 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..335		4/9 (44%)
		PHA03160	<464..530	CDD:165431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810