Protein Alignment CCT1 and CCT6A

DIOPT Version :9

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001753.1
• Gene: CCT6A / 908
• HGNCID: 1620
• Length: 531
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 142/547 - (25%)
• Similarity: 271/547 - (49%)
• Gaps: 32/547 - (5%)

  Fly     6 SPLSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEV 70
            :|.:.....|:..:|   |:.||..:.::::::|||.|..||||...||:.:|.||..:|..:::
Human     8 NPKAEVARAQAALAV---NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQI 69

  Fly    71 EHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYI 135
            :||.|.::.::|..||:..||||||.|::..||||.||..:.:.:||..|..|:..|.::|.:::
Human    70 QHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFL 134

  Fly   136 SEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINV 200
            .|...:  .|:.|::||::|:||:.:|:....|:..:..|||:..::|..|    ....:..|.:
Human   135 EEVKVS--REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD----EPIDLFMIEI 193

  Fly   201 LKAHGKSARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEA 265
            ::...||..::.||.|..|:.......|.|::.:|.|...:.||:..|.::.........::.|.
Human   194 MEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREK 258

  Fly   266 IRARELDITKERINMIL-------GTGVN--VVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKI 321
            :...|....::|:..|:       |....  ||:...|:|...:....:.|.:|:||.|:.:::.
Human   259 LVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMER 323

  Fly   322 IAKATGAAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDF 386
            :..|.|...:.|..::..:      .:|.|..|.:..:.:::...|:......:.:::::|||..
Human   324 LTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKH 382

  Fly   387 YCDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVI 451
            ...:::.:|.|.|..||..::...||.|.|.||.|::..|.....|:..|.||.:..||.:||:|
Human   383 TLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLII 447

  Fly   452 PKTLSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKS 516
            ||.|:.|:..|..:.:.|:::.|:.|.        :..|:||..|......:.||.:....|.:.
Human   448 PKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVDLNTGEPMVAAEVGVWDNYCVKKQL 504

  Fly   517 LKFATEAAITILRIDDMIKLNPEDKSG 543
            |...|..|..||.:|::::.......|
Human   505 LHSCTVIATNILLVDEIMRAGMSSLKG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	140/534 (26%)
CCT6A	NP_001753.1	chap_CCT_zeta	3..530	CDD:274088	141/544 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810