Protein Alignment CCT1 and CCT5

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_012598.1
• Gene: CCT5 / 853527
• SGDID: S000003825
• Length: 562
• Species: Saccharomyces cerevisiae
• Alignment Length: 535
• Identity: 172/535 - (32%)
• Similarity: 293/535 - (54%)
• Gaps: 33/535 - (6%)

  Fly    14 RQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVL 78
            ||.|...:..:::||.|:::|:|:||||.||||:|:...|::|:||||||||..:|:::..||:|
Yeast    40 RQHGLEAKKSHILAARSVASIIKTSLGPRGLDKILISPDGEITITNDGATILSQMELDNEIAKLL 104

  Fly    79 VELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISE---HLT 140
            |:|::.||:|:|||||.||:||:.||..|.||:::.|||..|.:|:..|.|.|...:.|   .::
Yeast   105 VQLSKSQDDEIGDGTTGVVVLASALLDQALELIQKGIHPIKIANGFDEAAKLAISKLEETCDDIS 169

  Fly   141 APVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHG 205
            |..|||.||.|:..||||:.|||:..|.:.|:.|.|:|..:|...|.:.      ...:::|..|
Yeast   170 ASNDELFRDFLLRAAKTSLGSKIVSKDHDRFAEMAVEAVINVMDKDRKD------VDFDLIKMQG 228

  Fly   206 K---SARESVLIPGYALNCTIASQQMPKKIV------NAKIACLDFSLQKTKMKMGVQVLINDPD 261
            :   |..:|.||.|..|:...:..||||.::      ..|:|.|....:..|.|...::.|:..:
Yeast   229 RVGGSISDSKLINGVILDKDFSHPQMPKCVLPKEGSDGVKLAILTCPFEPPKPKTKHKLDISSVE 293

  Fly   262 KLEAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKAT 326
            :.:.::..|.|..||.|:.:...|.:||:...|.||......::....|||.|...:|:.||.:|
Yeast   294 EYQKLQTYEQDKFKEMIDDVKKAGADVVICQWGFDDEANHLLLQNDLPAVRWVGGQELEHIAIST 358

  Fly   327 GAAFITSLTNMDGEESFDASMVGEAAEVAQERI--CDDELILIKGTKARAAASIILRGPNDFYCD 389
            ....:....::..::      :|..:.:.::..  ..|.:::|:.:|.....:..:||.|....|
Yeast   359 NGRIVPRFQDLSKDK------LGTCSRIYEQEFGTTKDRMLIIEQSKETKTVTCFVRGSNKMIVD 417

  Fly   390 EMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKT 454
            |.||::||:||||:.:::..:||.|||..|..:|:.:...|......:|.|...||::|..||.|
Yeast   418 EAERALHDSLCVVRNLVKDSRVVYGGGAAEVTMSLAVSEEADKQRGIDQYAFRGFAQALDTIPMT 482

  Fly   455 LSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKF 519
            |:.|:..|....::.|:    |.|.|.:.|::   |:|.:.....|.|:..|::|.:.|.:.:..
Yeast   483 LAENSGLDPIGTLSTLK----SKQLKEKISNI---GVDCLGYGSNDMKELFVVDPFIGKKQQILL 540

  Fly   520 ATEAAITILRIDDMI 534
            ||:....||:||::|
Yeast   541 ATQLCRMILKIDNVI 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	172/535 (32%)
CCT5	NP_012598.1	TCP1_epsilon	23..555	CDD:239455	171/533 (32%)