Protein Alignment CCT1 and HSP60

DIOPT Version :9

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_013360.1
• Gene: HSP60 / 850963
• SGDID: S000004249
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 615
• Identity: 128/615 - (20%)
• Similarity: 240/615 - (39%)
• Gaps: 155/615 - (25%)

  Fly    17 GASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLL----EVEHPAAKV 77
            |...|...:....:::..|.::|||.|.:.::....|...:|.||.|:.:.:    :.|:..||:
Yeast    30 GVEGRASLLKGVETLAEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKDKFENMGAKL 94

  Fly    78 LVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEH---- 138
            |.|:|...:|..||||||..:|...:...:.:.|....:|..:..|.::|.::..:::|.:
Yeast    95 LQEVASKTNEAAGDGTTSATVLGRAIFTESVKNVAAGCNPMDLRRGSQVAVEKVIEFLSANKKEI 159

  Fly   139 -----------------------LTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAA- 179
                                   |.:.::::|::.:|.|.:    .:.:..:.|....|..|..
Yeast   160 TTSEEIAQVATISANGDSHVGKLLASAMEKVGKEGVITIRE----GRTLEDELEVTEGMRFDRGF 220

  Fly   180 -QSVKITDPRGQAAYSIKAINVLKAHGKSARESVLIPGYALNCTIASQQMPKKIV------NAKI 237
             ....||||:.......|.:.:|.....|:.:.:| |  ||..:..|:: |..|:      .|..
Yeast   221 ISPYFITDPKSSKVEFEKPLLLLSEKKISSIQDIL-P--ALEISNQSRR-PLLIIAEDVDGEALA 281

  Fly   238 ACLDFSLQKTKMKMGVQVLINDPDKLEAIRAREL-DITKERINMILGTGVNVVLVSGG---VDDL 298
            ||:   |.|.:.::          |:.|::|... |..|..|.       ::.:::||   .::|
Yeast   282 ACI---LNKLRGQV----------KVCAVKAPGFGDNRKNTIG-------DIAVLTGGTVFTEEL 326

  Fly   299 CMK----YFVEAGAMAVRRVKKSDLKI-------------IAKATGAAFITSLTNMDGEESFDAS 346
            .:|    .....|:.....|.|.|..|             |.:..|:..||:..:.:.|:
Yeast   327 DLKPEQCTIENLGSCDSITVTKEDTVILNGSGPKEAIQERIEQIKGSIDITTTNSYEKEK----- 386

  Fly   347 MVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHDALCVVKRVLESKKV 411
                    .|||     |..:.|    ..|.|.:.|.::....|.:....|||...:..:| :.:
Yeast   387 --------LQER-----LAKLSG----GVAVIRVGGASEVEVGEKKDRYDDALNATRAAVE-EGI 433

  Fly   412 VAGGGCVEAALS-----IYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDLVAKL- 470
            :.|||......|     :.::||      .::|.:....|::....|.:..||.::.:.::.||
Yeast   434 LPGGGTALVKASRVLDEVVVDNF------DQKLGVDIIRKAITRPAKQIIENAGEEGSVIIGKLI 492

  Fly   471 --------RSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITI 527
                    :.|..|   |.|.:|:..||:.....|||    :|:::  .|.:.||...||.||
Yeast   493 DEYGDDFAKGYDAS---KSEYTDMLATGIIDPFKVVR----SGLVD--ASGVASLLATTEVAI-- 546

  Fly   528 LRIDDMIKLNPEDKSGKSYADACAAGELDG 557
              :|     .||..:      |..||.:.|
Yeast   547 --VD-----APEPPA------AAGAGGMPG 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	122/594 (21%)
HSP60	NP_013360.1	GroEL	25..548	CDD:239460	121/587 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810