DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT1 and TCP-1

DIOPT Version :9

Sequence 1:	NP_524450.2	Gene:	CCT1 / 42649	FlyBaseID:	FBgn0003676	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_188640.1	Gene:	TCP-1 / 821544	AraportID:	AT3G20050	Length:	545	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	357/544 - (65%)
Similarity:	449/544 - (82%)	Gaps:	0/544 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTLASPLSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATIL 65
            ||..|....|:|.||||..||||||||..::|||||:|||||||||||||||||||:||||||||
plant     1 MSISAQNPDISGDRQSGQDVRTQNVMACQAVSNIVKTSLGPVGLDKMLVDDIGDVTITNDGATIL 65

  Fly    66 RLLEVEHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKE 130
            |:|||||||||||||||:|||.|||||||||||:||||||.|::||:.||||||||||||:|.:|
plant    66 RMLEVEHPAAKVLVELAELQDREVGDGTTSVVIVAAELLKRANDLVRNKIHPTSIISGYRLAMRE 130

  Fly   131 ACKYISEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSI 195
            :||||.|.|...|::||:..|||.||||||||:|..|::||:.:||:|..|||:|:.||:..|.|
plant   131 SCKYIEEKLVTKVEKLGKVPLINCAKTSMSSKLISGDSDFFANLVVEAVLSVKMTNQRGEIKYPI 195

  Fly   196 KAINVLKAHGKSARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDP 260
            |.||:|||||:|||:|.|:.|||||...|:|.||.::..||||||||:||||||::||||::|||
plant   196 KGINILKAHGQSARDSYLLNGYALNTGRAAQGMPLRVSPAKIACLDFNLQKTKMQLGVQVVVNDP 260

  Fly   261 DKLEAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKA 325
            .:||.||.||.|:|||||..:|..|.||:|.:.|:||:.:||||||||:|||||:|.|::.:|||
plant   261 RELEKIRQREADMTKERIEKLLKAGANVILTTKGIDDMALKYFVEAGAIAVRRVRKEDMRHVAKA 325

  Fly   326 TGAAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDE 390
            |||..:|:..:|:|||:||.:.:|.|.||.:|||.||::|||||||..:|.|:||||.||:..||
plant   326 TGATLVTTFADMEGEETFDPAHLGSADEVVEERIADDDVILIKGTKTSSAVSLILRGANDYMLDE 390

  Fly   391 MERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTL 455
            |||::|||||:|||.|||..||||||.||:|||:|||:.||:|.|||||||||||.:||:|||.|
plant   391 MERALHDALCIVKRTLESNTVVAGGGAVESALSVYLEHLATTLGSREQLAIAEFADALLIIPKVL 455

  Fly   456 SVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFA 520
            :||||||||:||||||:||:::|||.::......||||:.|.:|:|.:|||:||||||:|.::||
plant   456 AVNAAKDATELVAKLRAYHHTAQTKADKKHYSSMGLDLVNGTIRNNLEAGVIEPAMSKVKIIQFA 520

  Fly   521 TEAAITILRIDDMIKLNPEDKSGK 544
            ||||||||||||||||..::..|:
plant   521 TEAAITILRIDDMIKLVKDESQGE 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	352/525 (67%)
TCP-1	NP_188640.1	TCP1_alpha	12..538	CDD:239451	352/525 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	669	1.000	Domainoid score	I20
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5656
Inparanoid	1	1.050	708	1.000	Inparanoid score	I129
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D335406at2759
OrthoFinder	1	1.000	-	-		FOG0005251
OrthoInspector	1	1.000	-	-		oto3905
orthoMCL	1	0.900	-	-		OOG6_101890
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3773
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840