Protein Alignment CCT1 and Bbs10

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001102756.1
• Gene: Bbs10 / 500832
• RGDID: 1560748
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 632
• Identity: 121/632 - (19%)
• Similarity: 230/632 - (36%)
• Gaps: 168/632 - (26%)

  Fly    24 NVMAALSISNIVKS----SLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQL 84
            :|.|||.::.::::    .:||.|...:.....|:|.::.||..:|..|.:|||.|:::|.....
  Rat     6 SVTAALRVAEVLETIANRCVGPEGGLVLCTKPTGEVLLSRDGGCLLEALHLEHPLARMIVACVSS 70

  Fly    85 QDEEVGDGTTSVVILAAELLKNADEL-VKQKIHPTS-IISGYRIACKEACKY------------- 134
            ..::.|||..:.:|....||:....: .|:|...|| .|..:....|..|::
  Rat    71 HLKKTGDGAKTFIIFLCHLLRGLHAIGEKEKDSFTSEDIQSHERHWKNCCQWKSISRALLRFQTQ 135

  Fly   135 -----ISEHL----------TAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKI 184
                 :.:||          :|....|.|.||..:.:.....::...:..|.|.::.|
  Rat   136 TLGCIVDQHLSRHYLSAFSSSAEGRTLCRRSLELLLEPYFCGRVGRNNHRFISQLMCD------- 193

  Fly   185 TDPRGQAAYSIKAINVLKAHGKSARESVLIPGYALNC----TIASQQMP---KKIVNAKIACLDF 242
                    |..|.:        :....:.:..:..||    .:....:|   .:||:..:...||
  Rat   194 --------YVFKCM--------ACESGIEVFEFLDNCFVELNVGVTGLPVSESRIVDGLVLPRDF 242

  Fly   243 S-----------------LQKTKMKMGVQVLINDPDKLEAIRARELDITKERINMILGTGVNVVL 290
            |                 ||........:.:::...:.:|.::..:|.||..:|.:....|.::|
  Rat   243 SVYCPADGGIRMVIVTEILQPLFSSSSSEFVLDSETQFQASQSWIMDRTKTVMNHLRSHNVKLLL 307

  Fly   291 VSGGVDDLCMKYFVEAGAMA-VRRVKKSDLKIIAKATGAA--FITSLTNMDGEESFDASMVGEAA 352
            .|....|| :.|.....::: |..:...::.::.:.||.:  .:..|.:.           ...|
  Rat   308 SSVKQPDL-VTYCARLNSISVVECLSSEEVSLVQRITGLSPCVLPELASQ-----------CHIA 360

  Fly   353 EVAQERICDDELILIKG---------TKARAAASIILRGPNDFYCDEMERSVHDALCVVKR---- 404
            :.|..|.| ..||:..|         |.|.....::|.||......:.|.:.|.|..::::
  Rat   361 DSALVRFC-KPLIVRSGRYAHLGLVSTCAFVPHCVVLCGPVLGLVQQHESAFHGAFKMLRQLFTD 424

  Fly   405 -----VLESKK-----VVAGGGCVEAALSIYLENFATSLA-SREQLAIAEFAKSLLVIPKTLSVN 458
                 ::::|:     .:|.....|::.|.....:...:| ::::|   |....|.|.|:.
  Rat   425 LDLNCMIQTKERRNPSPLADSSNRESSHSPKTGKYQDVVAKNKDKL---ETQTRLEVYPRL---- 482

  Fly   459 AAKDATDLVAKLRSYH-----NSSQT-------KPERSDLKWTGLDLIEGVVRDNKKAGVLEPAM 511
            .|.|...:..||.|.|     :.|||       .||:|.:    :|..| |..:|...|  .|..
  Rat   483 GASDTELITCKLWSAHKETSIDPSQTNEIPKRLSPEKSRI----VDNCE-VFLENNPTG--NPTA 540

  Fly   512 SKIKSLKFATEAAITILRIDDMIKLNPEDKSGKSYA--------DAC 550
            ...:     ||.:...|::.|    ||    |:.|.        |.|
  Rat   541 EDTR-----TEMSFKHLQVAD----NP----GEGYTLPVTYKSPDTC 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	115/610 (19%)
Bbs10	NP_001102756.1	Cpn60_TCP1	13..>424	CDD:395068	79/446 (18%)