Protein Alignment CCT1 and Cct8l2

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001032883.1
• Gene: Cct8l2 / 499967
• RGDID: 1561536
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 518
• Identity: 126/518 - (24%)
• Similarity: 235/518 - (45%)
• Gaps: 46/518 - (8%)

  Fly    27 AALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQLQDEEVGD 91
            ||.::::|::|..||.||.|.||...|:...|...|.||:.||:|||||:.:.||||.|.|..||
  Rat    47 AAQTLASIIRSCYGPYGLQKFLVSAQGETVCTGHAAAILKALELEHPAARFVQELAQTQAENTGD 111

  Fly    92 GTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTA----PVDELGRDSLI 152
            ||..||:|...||:.|..|:...:.|..:...:..|..|.       |||    .:..||.....
  Rat   112 GTAFVVLLTEALLEQAQYLLWAGLTPAQLREAFVTATAEV-------LTALPSLAICSLGPLEDP 169

  Fly   153 NIAKTSMSSKIIGADAEFFSAMVVDAAQSVKIT-DPRGQAAYSIKAINVLKAHGKSARESVLIPG 216
            :.|..|:.|....::||:.:.:|   ||:..|: :|.|  ::..::|.|....|....:|.:|||
  Rat   170 SWALYSVMSTHTLSNAEYLTKLV---AQACWISREPNG--SFKPESIVVCILQGGILTDSRIIPG 229

  Fly   217 YALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAIRARELDITKERINMI 281
            .|: |.....:..:.:.:|::|..:.....:.......:.::.|::|...|.:...:..|...:.
  Rat   230 IAI-CGKLCGRKTEVLNDARVALFNCPFGPSNPFAPATLRLSSPEELIRFRKQTEQVEMEIAELA 293

  Fly   282 LGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLTNMDGEESFDAS 346
            : .|:||.:|.|.|::..:......|.|.::...:.::..::...|...:..:        ....
  Rat   294 M-MGINVAVVLGEVNERSVDQADYCGVMVIQVKSRKEIVYLSDKLGVPLLNRI--------LPPL 349

  Fly   347 MVGEAAEVAQERICDDELILIKGTKARAA-ASIILRGPNDFYCDEMERSVHDALCVVKRVLESKK 410
            ..|:..:|.:....:..||:.:..:..|. .|::||||........|::|:..:....::.:..:
  Rat   350 EPGKCHKVYRMEFGESALIMFEWEREIAPFLSVVLRGPTIQGLRGAEQAVYYGIDAFSQLCQDPR 414

  Fly   411 VVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDLVAKLRSYHN 475
            ::.|.|..|.||:..|.:..:.|.....||...||::|..:||||:.||...|..::|::..||.
  Rat   415 LLPGAGATEMALARMLVDKGSRLDGPNGLAFQAFAQALSSLPKTLAENAGLAAQSVLAEMSGYHQ 479

  Fly   476 SSQTKPERSDLKWTGLDLIEGVVRDN----KKAGVLEPAMSKIKSLKFATEAAITILRIDDMI 534
            :.              :.:.||..|.    .:.|:.:...:|.:.|:..|.....::.:|.:|
  Rat   480 AG--------------NFVIGVGTDGLVNVAQEGIWDILRTKAQGLQAVTGLVQQLVTVDQII 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	126/518 (24%)
Cct8l2	NP_001032883.1	chaperonin_like	34..531	CDD:351886	126/518 (24%)