Protein Alignment CCT1 and Cct5

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001004078.1
• Gene: Cct5 / 294864
• RGDID: 735161
• Length: 541
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 173/529 - (32%)
• Similarity: 289/529 - (54%)
• Gaps: 25/529 - (4%)

  Fly    13 TRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKV 77
            :|..|......::|||.:::|.:::||||.|||||:||..|||||||||||||.:::|:|..||:
  Rat    26 SRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKL 90

  Fly    78 LVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKY---ISEHL 139
            :|||::.||:|:|||||.||:||..||:.|::|:.:.|||..|..||..|.:.|.::   ||:::
  Rat    91 MVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLDKISDNV 155

  Fly   140 TAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAH 204
            .  ||....:.||..|||::.||::.:.....:.:.|:|..:|...:.|.      ....::|..
  Rat   156 L--VDINNPEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRD------VDFELIKVE 212

  Fly   205 GK---SARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAI 266
            ||   ...::.||.|..::...:..||||:::|||||.|....:..|.|...::.:...:..:|:
  Rat   213 GKVGGRLEDTKLIKGVIVDKDFSHPQMPKEVLNAKIAILTCPFEPPKPKTKHKLDVTSVEDYKAL 277

  Fly   267 RARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFI 331
            :..|.:..:|.|..|..||.|:.:...|.||......::.|..|||.|...::::||.|||...:
  Rat   278 QKYEKEKFEEMIAQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIV 342

  Fly   332 TSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVH 396
            ...:.:..|:...|.:|.|.:....:    |::::|:..|...|.:|.:||.|....:|.:||:|
  Rat   343 PRFSELTSEKLGFAGVVREISFGTTK----DKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLH 403

  Fly   397 DALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAK 461
            |||||::.::...:||.|||..|.:.::.:...|....:.||.|:..||.:|.|||..||.|:..
  Rat   404 DALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGM 468

  Fly   462 DATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAIT 526
            :....:.::|    :.|.|.....|   |:|.:.....|.:...|:|..:.|.:.:..||:....
  Rat   469 NPIQTMTEVR----ARQVKESNPAL---GIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRM 526

  Fly   527 ILRIDDMIK 535
            ||:|||:.|
  Rat   527 ILKIDDIRK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	173/529 (33%)
Cct5	NP_001004078.1	TCP1_epsilon	10..535	CDD:239455	172/527 (33%)