Protein Alignment CCT1 and CCT3

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: XP_312164.4
• Gene: CCT3 / 1273209
• VectorBaseID: AGAMI1_003261
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 549
• Identity: 176/549 - (32%)
• Similarity: 296/549 - (53%)
• Gaps: 30/549 - (5%)

  Fly    14 RQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVL 78
            |:||..|:.:|:.|..:|::::::.|||..:.|||:|.:|.:.:||||..|||.:.|:|||||.:
Mosquito    17 RESGRKVQLENINAGKTIADLIRTCLGPQAMMKMLMDPMGGIVMTNDGNAILREITVQHPAAKSM 81

  Fly    79 VELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTAPV 143
            :|:|:.||||||||||||::||.|:|..|::.::|:||||.||..||.|.::..:.:.:.::..:
Mosquito    82 IEIARTQDEEVGDGTTSVIVLAGEMLAVAEQFLQQQIHPTVIIRAYREALEDMVRILQDEVSIEL 146

  Fly   144 DELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKA-INVLKAHGKS 207
            |...:..|..:.|:.:.:|.:|..::....:.:||.::|.:|: .|:....||. ..|.|..|.|
Mosquito   147 DRSDKKRLAEVVKSCVGTKFVGRWSDLAVRIALDAVETVSLTE-NGRTEIDIKKYAKVEKIPGGS 210

  Fly   208 ARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQV-LINDPDKLEAIRAREL 271
            ..:|.::.|..||..:...:|.:.|...:|..||..|:..|.:....| ::.|.|..:.::..|.
Mosquito   211 IDDSCVLRGIMLNKDVTHPKMRRYIEKPRIVLLDCPLEYKKGESQTNVEIVGDQDFTKLLQIEEE 275

  Fly   272 DITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFIT---S 333
            .:.: ....|:....:||....||.||...:.::||..|:||::|:|...:|:|.||..:.   .
Mosquito   276 HVAR-LCEDIIAVKPDVVFTEKGVSDLAQHFLMKAGITAIRRLRKTDNNRLARACGATIVNRTEE 339

  Fly   334 LTNMDGEESFDASMVGEAAEVAQ-ERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHD 397
            ||..|         ||..|.:.: :::.|:....:...:...|.:|:|||.:....:|.||::.|
Mosquito   340 LTEKD---------VGTGAGLFEIKKMGDEYFCFVTECEDPKACTILLRGASKDVLNETERNLQD 395

  Fly   398 ALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKD 462
            ||.|.:.::...|::.|||.||.|:|..|.|      .:.|......|::|.:||:||:.|...:
Mosquito   396 ALHVARNLMLDPKLLPGGGAVEMAVSQALTN------KQIQGPYRAVAQALEIIPRTLAQNCGAN 454

  Fly   463 ATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITI 527
            ....:..||:.|.|.....  ....| |:|...|.:.|.|:..:.||...|::..|.|.|.||.:
Mosquito   455 TIRTLTALRAKHASHPAAD--GPCTW-GIDGETGQLVDMKEKNIWEPLSVKLQVYKTAVETAILL 516

  Fly   528 LRIDDMI---KLNPEDKSGKSYADACAAG 553
            |||||::   |...:|.||.|.| |.|||
Mosquito   517 LRIDDIVSGSKKRGDDGSGPSPA-AAAAG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	167/532 (31%)
CCT3	XP_312164.4	chap_CCT_gamma	7..529	CDD:274085	167/531 (31%)