Protein Alignment CCT1 and Cct5

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_031663.1
• Gene: Cct5 / 12465
• MGIID: 107185
• Length: 541
• Species: Mus musculus
• Alignment Length: 533
• Identity: 177/533 - (33%)
• Similarity: 290/533 - (54%)
• Gaps: 33/533 - (6%)

  Fly    13 TRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKV 77
            :|..|......::|||.:::|.:::||||.|||||:||..||||:||||||||.:::|:|..||:
Mouse    26 SRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGATILSMMDVDHQIAKL 90

  Fly    78 LVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKY---ISEHL 139
            :|||::.||:|:|||||.||:||..||:.|::|:.:.|||..|..||..|.:.|.::   ||:.:
Mouse    91 MVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLDKISDKV 155

  Fly   140 TAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAH 204
            .  ||....:.||..|||::.||:|.:.....:.:.|:|..:|...:.|.      ....::|..
Mouse   156 L--VDINNPEPLIQTAKTTLGSKVINSCHRQMAEIAVNAVLTVADMERRD------VDFELIKVE 212

  Fly   205 GK---SARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQ----KTKMKMGVQVLINDPDK 262
            ||   ...::.||.|..::...:..|||||:|:||||.|....:    |||.|:.|..:    :.
Mouse   213 GKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKTKHKLDVMSV----ED 273

  Fly   263 LEAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATG 327
            .:|::..|.:..:|.|..|..||.|:.:...|.||......::.|..|||.|...::::||.|||
Mouse   274 YKALQKYEKEKFEEMIKQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIATG 338

  Fly   328 AAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEME 392
            ...:...:.:..|:...|.:|.|.:....:    |::::|:..|...|.:|.:||.|....:|.:
Mouse   339 GRIVPRFSELTSEKLGFAGVVQEISFGTTK----DKMLVIEKCKNSRAVTIFIRGGNKMIIEEAK 399

  Fly   393 RSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSV 457
            ||:||||||::.::...:||.|||..|.:.::.:...|....:.||.|:..||.:|.|||..||.
Mouse   400 RSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSE 464

  Fly   458 NAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATE 522
            |:..:....:.::|    :.|.|.....|   |:|.:.....|.:...|:|..:.|.:.:..||:
Mouse   465 NSGMNPIQTMTEVR----ARQVKESNPAL---GIDCLHKGSNDMQYQHVIETLIGKKQQISLATQ 522

  Fly   523 AAITILRIDDMIK 535
            ....||:|||:.|
Mouse   523 MVRMILKIDDIRK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	177/533 (33%)
Cct5	NP_031663.1	TCP1_epsilon	10..535	CDD:239455	176/531 (33%)