Protein Alignment Nrx-1 and CG34370

DIOPT Version :9

• Sequence 1: NP_001262840.1
• Gene: Nrx-1 / 42646
• FlyBaseID: FBgn0038975
• Length: 1847
• Species: Drosophila melanogaster
• Sequence 2: NP_001097404.2
• Gene: CG34370 / 5740565
• FlyBaseID: FBgn0085399
• Length: 952
• Species: Drosophila melanogaster
• Alignment Length: 635
• Identity: 121/635 - (19%)
• Similarity: 203/635 - (31%)
• Gaps: 202/635 - (31%)

  Fly   110 SQNSFYTFRKWYTGLNGTLELEFKTEQPNGLVLYTDDGGTYDFFELKLVEGALRLRYNLGGGAQI 174
            |:..|.:...||.. |.:.....|......:.||      :..|.:..:|..: |:|. |...:.
  Fly   396 SEGIFLSIAHWYPP-NTSCSYHIKGHVGEIVRLY------FPSFRINRIESPI-LKYE-GDCGES 451

  Fly   175 ITVGRELHDG-HWHKVQVLRNDEQT-SLIVDGVSQQRSTKGKEFQF----GKFASNSDVYVGGMP 233
            :|:    :|. |....::::....| |..::.|....::.....||    |.: |.|.:|.....
  Fly   452 LTI----YDSDHADPARIIKTFCDTFSRPMEKVDFVSTSPSLYVQFDSKTGSY-SGSSLYYWAHY 511

  Fly   234 NWYSSKLALLALPSVIFEP----------RFRGAIRNLVYADQPGGSTRRQEIKQQRDIKCGDVP 288
            :::::......:|:.:.:.          |.|..:.:|:: .:.|||               ||.
  Fly   512 DFFNNTRFGDPVPNTLCDEVMYAWKHPGGRLRSPLNSLIF-KRTGGS---------------DVR 560

  Fly   289 CDHGELPARERPLRGVRGGNT---------TDACERNDPCQHGGICISTDSGPICECRNLEYDGQ 344
            |.:..:..|....|.:...|:         ::||.|   |....:    |...|.|.|:...:..
  Fly   561 CQYKFVTDRRLYARAIIEVNSVSFKELPYNSNACTR---CHEERV----DKLVIWEERDKYQNNL 618

  Fly   345 YCEKEKAPSEATFRGTQFLSYDLGQTGAEPIVSAQDAISFYFRTRQPNGLLFYT---GHGTDYLN 406
            .|..:..|     |..:.:| ...|...|.||..|.||:.||  :.||.|...|   .||.....
  Fly   619 ACFCDNIP-----RAVRVIS-SADQMNLEMIVQGQHAITSYF--KNPNPLFEATYEFAHGPLCGP 675

  Fly   407 LAL---RDGGV----SLTMGLANGKQ---EMHIKPSKVRFDDHQWH-KVTVHRRIQEISSITSFC 460
            :.|   .||.:    ...:.:.:|..   |.|.:..|.     .|. ||...|.:
  Fly   676 ITLGPSPDGELVFPYKKALAMVSGPMAPPEHHYRREKC-----IWELKVAAQRDL---------- 725

  Fly   461 RLVTVVDDVYTDHSHIAGKFTMLSSSRVYVGGAVNPRALLGARVHTNFVGCLRKVEFSADTLNLN 525
             .:.:....:.|.|..:.|.      .||:.|.:.||          ||.|...:..:.|...|.
  Fly   726 -WLNLEKARFADRSCDSAKI------EVYLAGRLEPR----------FVVCPENISLARDLPILT 773

  Fly   526 LIDLAKSGSKLIQVAGNLEYQCPSGDPQDPVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGI 590
            ..:|..:|:                                                 .:||..:
  Fly   774 TAELGATGA-------------------------------------------------DQEPLPV 789

  Fly   591 IVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRASRRRVDDGDWHDLILRRNGRDAK 655
            ::..||..||......|:..||      .||.             |..||.....:|:..|
  Fly   790 LIQYTGDGQPGRNIFRLVWTEL------FHLP-------------RNPDGSLAASLLQDGG---- 831

  Fly   656 VSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQ 705
                   .|||.||| |.:.:..|:...|:      .:.|....|:||.|
  Fly   832 -------CDFRCPGD-TEVCIPKHLLCNGI------ANCPNVTHTSTLSQ 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrx-1	NP_001262840.1	LamG	110..263	CDD:238058	29/168 (17%)
		EGF_CA	311..347	CDD:238011	8/35 (23%)
		Laminin_G_2	386..517	CDD:280389	29/144 (20%)
		LamG	555..716	CDD:238058	30/151 (20%)
		EGF	746..777	CDD:278437
		Laminin_G_2	814..945	CDD:280389
		LamG	988..1136	CDD:238058
		EGF	1164..1195	CDD:278437
		Laminin_G_2	1233..1356	CDD:280389
CG34370	NP_001097404.2	CUB	88..195	CDD:238001
		CUB	244..363	CDD:238001
		CUB	407..509	CDD:238001	22/115 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444880
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930