DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrx-1 and CG7631

DIOPT Version :9

Sequence 1:	NP_001262840.1	Gene:	Nrx-1 / 42646	FlyBaseID:	FBgn0038975	Length:	1847	Species:	Drosophila melanogaster
Sequence 2:	NP_609760.1	Gene:	CG7631 / 34919	FlyBaseID:	FBgn0028945	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	67/297 - (22%)
Similarity:	97/297 - (32%)	Gaps:	91/297 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 APHSATYQDNYADAAMTA-RTRPSMDMDQQRNRNQAELRLLPAQRTSTSAFESPDLRFNKARRRR 66
            ||.:..|.:  .|..:|| ..:..||:|..||...:|.|..|                |.....|
  Fly    21 APFNTHYDE--TDPELTAGYFQGDMDVDYARNGQLSETRRWP----------------NATVPYR 67

  Fly    67 RSEQVPPVVVEYRRSYRVLIVSALLVSLAASFVTLSAGFQL----DGSQNSFYTFRKWYTGLNGT 127
            .||:.....|||             :.|...|:..|:..:.    :..:|..:...
  Fly    68 ISEEFDAPHVEY-------------IKLGMQFIEYSSCIRFVPADEDEENYLFVLP--------- 110

  Fly   128 LELEFKTEQPNGLVLYTDDGGTYDFFELKLVEGALRLR-YNLGGGAQIITVGRE-LHDGHWHKVQ 190
                 .|...:..|.|.....|     :||..|:|... :.||      |:..| ||...:|..|
  Fly   111 -----STSGCSSKVGYQPGERT-----VKLKPGSLDTGCFKLG------TIQHELLHTLGFHHQQ 159

  Fly   191 VLRN-DEQTSLIVDGVSQQRSTKGKEFQFGKFASNSDVYVG--GMPNWYSSKLALLALPSVIFEP 252
            ...| ||...::.:.:|:     |.|..|.|:..:.   ||  ..|..|.|   :|...|:.|..
  Fly   160 CSPNRDEFVKIVEENISE-----GHEKNFVKYEEDE---VGDFDQPYDYGS---ILHYSSLAFSI 213

  Fly   253 RFRGAIRNLVYADQPGGSTRRQEIKQQR------DIK 283
            .....|    .|..|.|    ||...||      |:|
  Fly   214 NGEATI----VALNPEG----QEQMGQRLMMSDTDVK 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrx-1	NP_001262840.1	LamG	110..263	CDD:238058	34/157 (22%)
		EGF_CA	311..347	CDD:238011
		Laminin_G_2	386..517	CDD:280389
		LamG	555..716	CDD:238058
		EGF	746..777	CDD:278437
		Laminin_G_2	814..945	CDD:280389
		LamG	988..1136	CDD:238058
		EGF	1164..1195	CDD:278437
		Laminin_G_2	1233..1356	CDD:280389
CG7631	NP_609760.1	Astacin	57..251	CDD:279708	55/259 (21%)
CG7631	NP_609760.1	ZnMc_astacin_like	61..248	CDD:239807	53/239 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444921
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930