Protein Alignment AP-2mu and AP1M1

DIOPT Version :9

• Sequence 1: NP_001163686.1
• Gene: AP-2mu / 42642
• FlyBaseID: FBgn0263351
• Length: 437
• Species: Drosophila melanogaster
• Sequence 2: NP_001123996.1
• Gene: AP1M1 / 8907
• HGNCID: 13667
• Length: 435
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 174/446 - (39%)
• Similarity: 260/446 - (58%)
• Gaps: 32/446 - (7%)

  Fly     5 LFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHIKRANIWLAAV 68
            ::|.:.||:|||.|.||.|:..:.|:.|...::...:: :.||:.......|..||..|::|.|.
Human     6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVAT 70

  Fly    69 TKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGYPQNTDSGTLKTFI 133
            :|:|...::||.||.|:::|...||.::.||:|::|||:|||||||::||||||.|||..|:.:|
Human    71 SKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYI 135

  Fly   134 TQQGIKSATKEEQMQITSQVTGQIGWRREGIKYRRNELFLDVLEYVNLL------------MSPQ 186
            ||:|.|..|...:...|  ||..:.||.||||||:||:||||:|.||||            :|..
Human   136 TQEGHKLETGAPRPPAT--VTNAVSWRSEGIKYRKNEVFLDVIESVNLLGKYPGVGWLGHTVSAN 198

  Fly   187 GQVLSAHVAGKVVMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETSRSGKPVVVIDDCQFH 251
            |.||.:.:.|.:.|:.:||||||.:.|:|||::.::.|||.|.:.|            ::|.:||
Human   199 GNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVE------------LEDVKFH 251

  Fly   252 QCVKLSKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFKPS 316
            |||:||:||.:.:|||||||||||||.||....:.....:..::.:...:::|..:..||.||..
Human   252 QCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRR 316

  Fly   317 LLGQKIEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKK 381
            .....:|:.||.|.:....:.....|..|:....:.|||.||...|.||..:.|...|...:.:.
Human   317 STANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAED 381

  Fly   382 KWTRPPISMNFEVP-FAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETR 436
            |..:||||:.||:| |..||.:|||||:.|.    |.:..:.|||||.::|.|:.|
Human   382 KEGKPPISVKFEIPYFTTSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2mu	NP_001163686.1	AP2_Mu_N	1..140	CDD:341440	57/135 (42%)
		AP-2_Mu2_Cterm	166..436	CDD:271159	105/282 (37%)
AP1M1	NP_001123996.1	AP1_Mu_N	4..142	CDD:341439	57/135 (42%)
		AP-1_Mu1A_Cterm	153..434	CDD:271166	114/297 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D725236at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920