DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AP-2mu and HAP13

DIOPT Version :9

Sequence 1:	NP_001163686.1	Gene:	AP-2mu / 42642	FlyBaseID:	FBgn0263351	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_176277.1	Gene:	HAP13 / 842372	AraportID:	AT1G60780	Length:	428	Species:	Arabidopsis thaliana

Alignment Length:	443	Identity:	163/443 - (36%)
Similarity:	262/443 - (59%)	Gaps:	35/443 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHAR--QQVRSPVTNIARTSFFHIKRANIWLAA 67
            ||:.:.||.||:.|.||.|:.....:.|...:|...  .|...||......::..::.:|::|..
plant     8 LFLLDIKGRVLVWRDYRGDVSAAQAERFFTKLIEKEGDSQSNDPVAYDNGVTYMFVQHSNVYLMI 72

  Fly    68 VTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGYPQNTDSGTLKTF 132
            .::||.|||.:..||.::::|.:.||.::.||::::|||::||||||::||||||.|::..|..|
plant    73 ASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQYTEARILSEF 137

  Fly   133 ITQQGIKSATKEEQMQITSQ----VTGQIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAH 193
            |       .|...:|::|.:    ||..:.||.|||:|::||:||||:|.||:|::..||::.:.
plant   138 I-------KTDAYRMEVTQRPPMAVTNAVSWRSEGIQYKKNEVFLDVIENVNILVNSNGQIVRSD 195

  Fly   194 VAGKVVMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETSRSGKPVVVIDDCQFHQCVKLSK 258
            |.|.:.|::||:||||||.|:||::::|::||...|.:           :.::|.:|||||:|::
plant   196 VVGALKMRTYLTGMPECKLGLNDRVLLEAQGRATKGKA-----------IDLEDIKFHQCVRLAR 249

  Fly   259 FETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFKPSLLGQKIE 323
            ||.:.:||||||||.|:||.||.:..:.....|...:....|:::|:.:..:|.||.......:|
plant   250 FENDRTISFIPPDGAFDLMTYRLSTQVKPLIWVEAQIESHSRSRVEMLIKARSQFKERSTATNVE 314

  Fly   324 VKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIEL----LETDTKKKWT 384
            :::|.|.:.|...:....|.|.|...::|:|||||...|.||..|.||..|    .|..|.::
plant   315 IELPVPTDASNPTVRTSLGSASYAPEKDALVWKIKSFPGNKEYMLRAEFHLPSITAEEATPER-- 377

  Fly   385 RPPISMNFEVP-FAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETR 436
            :.||.:.||:| |..||.:|||||:.|.    |.:..:.|||||..:|.||.|
plant   378 KAPIRVKFEIPYFTVSGIQVRYLKIIEK----SGYQALPWVRYITMAGEYELR 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-2mu	NP_001163686.1	AP2_Mu_N	1..140	CDD:341440	48/136 (35%)
AP-2mu	NP_001163686.1	AP-2_Mu2_Cterm	166..436	CDD:271159	104/274 (38%)
HAP13	NP_176277.1	AP1_Mu_N	6..145	CDD:341439	49/143 (34%)
HAP13	NP_176277.1	AP-1_Mu1_Cterm	156..426	CDD:271158	110/286 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D725236at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920