DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-2mu and AT5G46630

DIOPT Version :9

Sequence 1:	NP_001163686.1	Gene:	AP-2mu / 42642	FlyBaseID:	FBgn0263351	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_974895.1	Gene:	AT5G46630 / 834706	AraportID:	AT5G46630	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	414	Identity:	200/414 - (48%)
Similarity:	283/414 - (68%)	Gaps:	18/414 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHIKRANIWLAAVT 69
            ::..|.:|:|||:|.||||:|.|.|||||.:::..::....||..|...||.:::.:|:::..|.
plant     8 IYFLNLRGDVLINRTYRDDVGGNMVDAFRTHIMQTKELGNCPVRQIGGCSFVYMRISNVYIVIVV 72

  Fly    70 KQNVNAAMVFEFLLKIIEVMQSYF-GKISEENIKNNFVLIYELLDEILDFGYPQNTDSGTLKTFI 133
            ..|.|.|..|:|:::.:.:.:||| |...|:.|:|||||||||||||:|||||||.....||.:|
plant    73 SSNANVACGFKFVVEAVALFKSYFGGAFDEDAIRNNFVLIYELLDEIMDFGYPQNLSPEILKLYI 137

  Fly   134 TQQGIKS--ATKEEQMQI---TSQVTGQIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAH 193
            ||:|::|  ::|.:...:   |.||||.:||||||:.|::||:|||::|.||||||.:|.||...
plant   138 TQEGVRSPFSSKPKDKPVPNATLQVTGAVGWRREGLAYKKNEVFLDIVESVNLLMSSKGNVLRCD 202

  Fly   194 VAGKVVMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAET--SRSGKPVVVIDDCQFHQCVKL 256
            |.|||:||.:|||||:.|.|:||||       ||...||.::  ::||| .:.:||..|||||.|
plant   203 VTGKVLMKCFLSGMPDLKLGLNDKI-------GLEKESEMKSRPAKSGK-TIELDDVTFHQCVNL 259

  Fly   257 SKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFKPSLLGQK 321
            ::|.:|.::||:|||||||||:||.|:.::|||||:|.::|:|||:|||.|.:||.|...:....
plant   260 TRFNSEKTVSFVPPDGEFELMKYRITEGVNLPFRVLPTIKELGRTRMEVNVKVKSVFGAKMFALG 324

  Fly   322 IEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLET-DTKKKWTR 385
            :.||||.|..|:........|:|||..|.:.:||||::..|..|:.|||||||:.| ..||.|||
plant   325 VVVKIPVPKQTAKTNFQVTTGRAKYNPSIDCLVWKIRKFPGQTESTLSAEIELISTMGEKKSWTR 389

  Fly   386 PPISMNFEVP-FAPSGFKVRYLKV 408
            |||.|.|:|| |..||.:||:|||
plant   390 PPIQMEFQVPMFTASGLRVRFLKV 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-2mu	NP_001163686.1	AP2_Mu_N	1..140	CDD:341440	61/135 (45%)
AP-2mu	NP_001163686.1	AP-2_Mu2_Cterm	166..436	CDD:271159	126/247 (51%)
AT5G46630	NP_974895.1	AP-2_Mu2_Cterm	175..413	CDD:271159	124/245 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	285	1.000	Domainoid score	I379
eggNOG	1	0.900	-	-		E1_KOG0938
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3000
Inparanoid	1	1.050	416	1.000	Inparanoid score	I446
OMA	1	1.010	-	-		QHG53686
OrthoDB	1	1.010	-	-		D725236at2759
OrthoFinder	1	1.000	-	-		FOG0003937
OrthoInspector	1	1.000	-	-		oto3945
orthoMCL	1	0.900	-	-		OOG6_102976
Panther	1	1.100	-	-	LDO	PTHR10529
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2710
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840