Protein Alignment AP-2mu and ap1m3

DIOPT Version :10

• Sequence 1: NP_651049.3
• Gene: AP-2mu / 42642
• FlyBaseID: FBgn0263351
• Length: 437
• Species: Drosophila melanogaster
• Sequence 2: NP_001107913.2
• Gene: ap1m3 / 445244
• ZFINID: ZDB-GENE-040801-159
• Length: 423
• Species: Danio rerio
• Alignment Length: 434
• Identity: 173/434 - (39%)
• Similarity: 260/434 - (59%)
• Gaps: 20/434 - (4%)

  Fly     5 LFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVR-SPVTNIARTSFFHIKRANIWLAAV 68
            :|:.:.||:|||.|.|..:|..|.:|.|...::...::.. |||.....|.|..||.:|::|.|:
Zfish     6 IFILDLKGKVLICRNYMGNIDMNVIDNFMPIMMKREEEAELSPVVIHGSTHFLWIKHSNLYLVAM 70

  Fly    69 TKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGYPQNTDSGTLKTFI 133
            ||:|.|||:|:.||.|::||...||..:.||:|::|||.:|||:||::|||:||.|||..|..:|
Zfish    71 TKKNTNAALVYSFLYKLVEVFTEYFKSLEEESIRDNFVTVYELMDEVMDFGFPQTTDSKILLEYI 135

  Fly   134 TQQGIKSATKEEQMQITSQVTGQIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAHVAGKV 198
            ||||.|......:...|  ||..:.||.||||||:||:|:||:|.||||:|..|.||.:.:.|.:
Zfish   136 TQQGHKLEVGAPRPPAT--VTNAVSWRSEGIKYRKNEVFMDVIESVNLLVSATGSVLRSEILGCI 198

  Fly   199 VMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETSRSGKPVVVIDDCQFHQCVKLSKFETEH 263
            .:|..||||||.:.|:|||::.|..||        |.::|    |.::|.:|||||:||:||.:.
Zfish   199 KLKVVLSGMPELRLGLNDKVLFEITGR--------EKTKS----VELEDVKFHQCVRLSRFENDR 251

  Fly   264 SISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFKPSLLGQKIEVKIPT 328
            :|||||||||.|||.||....:.....:..::.:...:::|:||..:|.||.......:.:.:|.
Zfish   252 TISFIPPDGESELMSYRLNTTVKPLIWIESVIEKFSHSRVEIKVKARSQFKSRSTANNVSILVPV 316

  Fly   329 PLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMNFE 393
            |.:....:.....|:||:...::|:.|.||...|.||..:.|...|...::.:...:.||::.||
Zfish   317 PSDADSPKFKTTTGQAKWVPEKSAVEWNIKSFPGGKEFMMRAHFGLPSVESDELEGKRPITVKFE 381

  Fly   394 VP-FAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETR 436
            :| |..||.:|||||:.|.    |.:..:.|||||.:||.|:.|
Zfish   382 IPYFTVSGIQVRYLKIIEK----SGYQALPWVRYITQSGDYQLR 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2mu	NP_651049.3	AP2_Mu_N	1..140	CDD:341440	61/135 (45%)
		AP-2_Mu2_Cterm	166..436	CDD:271159	101/270 (37%)
ap1m3	NP_001107913.2	None