DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AP-2mu and stnB

DIOPT Version :9

Sequence 1:	NP_001163686.1	Gene:	AP-2mu / 42642	FlyBaseID:	FBgn0263351	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_001036318.2	Gene:	stnB / 4379834	FlyBaseID:	FBgn0016975	Length:	1262	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	91/436 - (20%)
Similarity:	164/436 - (37%)	Gaps:	95/436 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 FHIKRANIWLAAVTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGY 120
            |:.:|..:....|||               .|.:.:...|.::..|..::..:.|...::...|.
  Fly   809 FYKERPGVRPGQVTK---------------AERITNKLTKFAQYAIAGDYEGVKEFGSDLKKLGL 858

  Fly   121 PQNTDSGTLKTFITQQGIKSATKEEQMQITSQVTGQI----GWRREGIKYRRNELFLDVLEYVNL 181
            |......:.:.|    .|.|...|:..|.:..:...:    ..|...:.|:..|:.:..::.:.:
  Fly   859 PVEHAPQSSQLF----KIGSMNYEDMKQFSVCIEEALFKIPALRERALTYKMEEVQVTAVDEITV 919

  Fly   182 LMSPQGQVLSAHVAGKVVMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETSRSGKPV---- 242
            ....:|::|......::...::|:|||..:.|:||   |..:|:.:.|..:.      .||
  Fly   920 EQDFEGKILKQIARVRLFFLAFLTGMPTIELGVND---MWRQGKEVVGRHDI------IPVATEE 975

  Fly   243 -VVIDDCQFHQCVKLSKFETEHSISFIPPDGEF-ELMRYRT--TKDISLPFRVIPLVREVGRTKM 303
             :.::..:||..|...::|...:|.|.|||..: ||:|:|.  .|:..||.: :.....|...|:
  Fly   976 WIRLEAVEFHSVVNQKEYERTRTIKFQPPDANYIELLRFRVRPPKNRELPLQ-LKATWCVSGNKV 1039

  Fly   304 EVKV-VLKSNFKPSLLGQ----KIEVKIPTP---------------------------------- 329
            |::. :|...|....|||    .:.|:.|.|
  Fly  1040 ELRADILVPGFTSRKLGQIPCEDVSVRFPIPECWIYLFRVEKHFRYGSVKSAHRRTGKIKGIERI 1104

  Fly   330 ---LNTSGVQLI-CLKGKAKYKASENAIVWKIKRM----AGMKET-QLSAEIELLETDTKKKWTR 385
               ::|....|| ...|:|||:....||||:..|:    .|...| ||...:.|...|.......
  Fly  1105 LGAVDTLQESLIEVTSGQAKYEHHHRAIVWRCPRLPKEGQGAYTTHQLVCRMALTSYDQIPSELA 1169

  Fly   386 PPISMNFEVPFAPSGFKVRYLKVFEPKLNYSDHD--VVKWVRYIGR 429
            |...:.|.:|    ..:|.:..|....:..||.|  ..|:|||:.|
  Fly  1170 PYAFVEFTMP----ATQVSHTTVRSVSVQDSDGDEPPEKYVRYLAR 1211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AP-2mu	NP_001163686.1	AP2_Mu_N	1..140	CDD:341440	13/83 (16%)
AP-2mu	NP_001163686.1	AP-2_Mu2_Cterm	166..436	CDD:271159	74/322 (23%)
stnB	NP_001036318.2	Trypan_PARP	377..496	CDD:114603
stnB	NP_001036318.2	AP_MHD_Cterm	897..1219	CDD:299401	75/329 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940