DRSC/TRiP Functional Genomics Resources

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Protein Alignment AP-2mu and cm

DIOPT Version :9

Sequence 1:NP_001163686.1 Gene:AP-2mu / 42642 FlyBaseID:FBgn0263351 Length:437 Species:Drosophila melanogaster
Sequence 2:NP_001259302.1 Gene:cm / 31647 FlyBaseID:FBgn0000330 Length:415 Species:Drosophila melanogaster


Alignment Length:460 Identity:123/460 - (26%)
Similarity:210/460 - (45%) Gaps:70/460 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MIGGLFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFH---IKRAN 62
            ||..||:.|..|||.:.:.:|..:.|:..:.|    :.|::.....|..:..|..::   ::|..
  Fly     1 MIHSLFIVNSGGEVFLEKHWRSVVSRSVCEYF----LDAQRAAPYDVPPVIATPHYYLITVQRDT 61

  Fly    63 IWLAAVTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGYPQNTDSG 127
            :.|.|..||.|....|.|||.::::..|.|||..||..||:|:|::||||||:||.|:|..|:|.
  Fly    62 VSLVAACKQEVPPLFVIEFLHRVVDTFQDYFGDCSESVIKDNYVVVYELLDEMLDNGFPLATESN 126

  Fly   128 TLKTFITQQGI-----KSATKEEQMQITSQVTGQIG---WRREGIKYRRNELFLDVLEYVNLLMS 184
            .||..|....|     .:.|.:..:. |:..:||:.   |||.|::|..||.:.||:|.|:.::.
  Fly   127 ILKELIKPPNILRTIANTVTGKSNVS-TTLPSGQLSAVRWRRSGVRYTNNEAYFDVIEEVDAIID 190

  Fly   185 PQGQVLSAHVAGKVVMKSYLSGMPECKFG-INDKIVMESKGRGLSGNSEAETSRSGKPVVVIDDC 248
            ..|..:.|.:.|.:.....|||||:.... :|.::                          .||.
  Fly   191 KSGSTVFAEIQGHIDCCIKLSGMPDLTLSFMNPRL--------------------------FDDV 229

  Fly   249 QFHQCVKLSKFETEHSISFIPPDGEFELMRYRTTKD--ISLPFRVIPLVREVGRTKMEVKVVLKS 311
            .||.||:..::|.|..:|||||||.|.||.|..:..  :::|..:        |....:|...:.
  Fly   230 SFHPCVRYKRWEAERLLSFIPPDGNFRLMSYHISSQSVVAIPIYI--------RHNFSIKTGEQG 286

  Fly   312 NFKPSL-----LGQKIEVKIPTPLNTSGVQLICL----KGKAKYKASENAIVWKIKRMAGMKETQ 367
            ....::     ||:.:: |:...|......|.||    :||..:.:....:.|.:.|:...|...
  Fly   287 RLDLTIGPRNTLGRTVD-KVKLELTMPRCVLNCLLTPNQGKYTFDSVTKTLSWDVGRIDVSKLPN 350

  Fly   368 LSAEIELLETDTKKKWTRPPISMNFEV-PFAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSG 431
            :...:.:....|... ..|.:::.|:: ..|.||.||..|.::..|     :...|.|:|:.::|
  Fly   351 IRGSVSITPGTTNID-ANPSVNVQFQISQLAVSGLKVNRLDMYGEK-----YKPFKGVKYLTKAG 409

  Fly   432 LYETR 436
            .::.|
  Fly   410 KFQVR 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AP-2muNP_001163686.1 AP2_Mu_N 1..140 CDD:341440 50/146 (34%)
AP-2_Mu2_Cterm 166..436 CDD:271159 64/282 (23%)
cmNP_001259302.1 AP_MHD_Cterm 163..414 CDD:299401 68/291 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45439810
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10529
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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