DRSC/TRiP Functional Genomics Resources

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Protein Alignment AP-2mu and Ap1m1

DIOPT Version :9

Sequence 1:NP_001163686.1 Gene:AP-2mu / 42642 FlyBaseID:FBgn0263351 Length:437 Species:Drosophila melanogaster
Sequence 2:NP_001037704.1 Gene:Ap1m1 / 306332 RGDID:1307653 Length:423 Species:Rattus norvegicus


Alignment Length:434 Identity:175/434 - (40%)
Similarity:260/434 - (59%) Gaps:20/434 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQ-VRSPVTNIARTSFFHIKRANIWLAAV 68
            ::|.:.||:|||.|.||.|:..:.|:.|...::...:: :.||:.......|..||..|::|.|.
  Rat     6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVAT 70

  Fly    69 TKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGYPQNTDSGTLKTFI 133
            :|:|...::||.||.|:::|...||.::.||:|::|||:|||||||::||||||.|||..|:.:|
  Rat    71 SKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYI 135

  Fly   134 TQQGIKSATKEEQMQITSQVTGQIGWRREGIKYRRNELFLDVLEYVNLLMSPQGQVLSAHVAGKV 198
            ||:|.|..|...:...|  ||..:.||.||||||:||:||||:|.||||:|..|.||.:.:.|.:
  Rat   136 TQEGHKL
ETGAPRPPAT--VTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSI 198

  Fly   199 VMKSYLSGMPECKFGINDKIVMESKGRGLSGNSEAETSRSGKPVVVIDDCQFHQCVKLSKFETEH 263
            .|:.:||||||.:.|:|||::.::.|||.|.:.|            ::|.:|||||:||:||.:.
  Rat   199 KMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVE------------LEDVKFHQCVRLSRFENDR 251

  Fly   264 SISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFKPSLLGQKIEVKIPT 328
            :|||||||||||||.||....:.....:..::.:...:::|..|..||.||.......:|:.||.
  Rat   252 TISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPV 316

  Fly   329 PLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMNFE 393
            |.:....:.....|..|:....:.|||.||...|.||..:.|...|...:.:.|..:||||:.||
  Rat   317 PNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFE 381

  Fly   394 VP-FAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETR 436
            :| |..||.:|||||:.|.    |.:..:.|||||.::|.|:.|
  Rat   382 IPYFTTSGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AP-2muNP_001163686.1 AP2_Mu_N 1..140 CDD:341440 57/135 (42%)
AP-2_Mu2_Cterm 166..436 CDD:271159 106/270 (39%)
Ap1m1NP_001037704.1 AP1_Mu_N 4..142 CDD:341439 57/135 (42%)
AP-1_Mu1A_Cterm 153..422 CDD:271166 115/285 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D725236at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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