Protein Alignment AP-2mu and apm4

DIOPT Version :10

• Sequence 1: NP_651049.3
• Gene: AP-2mu / 42642
• FlyBaseID: FBgn0263351
• Length: 437
• Species: Drosophila melanogaster
• Sequence 2: NP_592921.1
• Gene: apm4 / 2541527
• PomBaseID: SPAC31A2.09C
• Length: 446
• Species: Schizosaccharomyces pombe
• Alignment Length: 450
• Identity: 176/450 - (39%)
• Similarity: 283/450 - (62%)
• Gaps: 19/450 - (4%)

  Fly     1 MIGGLFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHIKRANIWL 65
            ||.|||::|.||:.||.:.:|.|:.::..:.|||.:: .....|.|:.:|..:::.:.|..::::
pombe     1 MISGLFIFNLKGDTLICKTFRHDLKKSVTEIFRVAIL-TNTDYRHPIVSIGSSTYIYTKHEDLYV 64

  Fly    66 AAVTKQNVNAAMVFEFLLKIIEVMQSYFGKISEENIKNNFVLIYELLDEILDFGYPQNTDSGTLK 130
            .|:||.|.|..:|.|||..:|:.:..||||::|..:|:|...|:|||||::|:|..|.|:...|.
pombe    65 VAITKGNPNVMIVLEFLESLIQDLTHYFGKLNENTVKDNVSFIFELLDEMIDYGIIQTTEPDALA 129

  Fly   131 TFITQQGIK------SATKEEQMQI----TSQVTGQIGWRREGIKYRRNELFLDVLEYVNLLMSP 185
            ..::...:|      |..:....|:    :|::.|.:.|||.|||||:|.:::|::|.:|||:|.
pombe   130 RSVSITAVKKKGNALSLKRSHSSQLAHTTSSEIPGSVPWRRAGIKYRKNSIYIDIVERMNLLISS 194

  Fly   186 QGQVLSAHVAGKVVMKSYLSGMPECKFGINDKI---VMESKGRGLSGNSEAETSRSGKPVVVIDD 247
            .|.||.:.|:|.|.|::.|||||||:||:|||:   :.:|:.:..|.||...:|.:| ..|:::|
pombe   195 TGNVLRSDVSGVVKMRAMLSGMPECQFGLNDKLDFKLKQSESKSKSNNSRNPSSVNG-GFVILED 258

  Fly   248 CQFHQCVKLSKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSN 312
            |||||||:|.:||.||.|:|||||||.|||.||:.::|::|||::|:|.::.:.|:..::.::::
pombe   259 CQFHQCVRLPEFENEHRITFIPPDGEVELMSYRSHENINIPFRIVPIVEQLSKQKIIYRISIRAD 323

  Fly   313 FKPSLLGQKIEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLET 377
            : |..|...:..:||.|.|.........:|||.|:.|||.|.|||.|..|..|....||:||..|
pombe   324 Y-PHKLSSSLNFRIPVPTNVVKANPRVNRGKAGYEPSENIINWKIPRFLGETELIFYAEVELSNT 387

  Fly   378 DTKKKWTRPPISMNFEV-PFAPSGFKVRYLKVFEPKLNYSDHDVVKWVRYIGRSGLYETR 436
            ..::.|.:||||::|.: .|..||..|:||:|.||  :.|.:..:|||||..|:|..|.|
pombe   388 TNQQIWAKPPISLDFNILMFTSSGLHVQYLRVSEP--SNSKYKSIKWVRYSTRAGTCEIR 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP-2mu	NP_651049.3	AP2_Mu_N	1..140	CDD:341440	48/144 (33%)
		AP-2_Mu2_Cterm	166..436	CDD:271159	117/273 (43%)
apm4	NP_592921.1	AP2_Mu_N	1..139	CDD:341440	47/138 (34%)
		AP-2_Mu2_Cterm	175..445	CDD:271159	117/273 (43%)