Protein Alignment CG34376 and lola

DIOPT Version :10

• Sequence 1: NP_732741.1
• Gene: CG34376 / 42638
• FlyBaseID: FBgn0085405
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_788308.3
• Gene: lola / 44548
• FlyBaseID: FBgn0283521
• Length: 970
• Species: Drosophila melanogaster
• Alignment Length: 826
• Identity: 179/826 - (21%)
• Similarity: 271/826 - (32%)
• Gaps: 249/826 - (30%)

  Fly     1 MDDEFKLC--WKNFQDNIASGFQNLYDRGDLVDVTLACDGKLLHAHKIVLAICSPYFQEIFTTNP 63
            |||:.:.|  |.|.|..:.|.|..|.:...|||.|||.:||.|.|||:||:.|||||..:.....
  Fly     1 MDDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQY 65

  Fly    64 CKHPIIILKDVSFNIMMELLEFMYQGVVNVKHTELQSFMKIGQLLQIKGLATN------------ 116
            .||||.|||||.:..:..::::||:|.||:...:|.:.:|..:.||||||:.|
  Fly    66 DKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPES 130

  Fly   117 -----------------------------------SNSSPGSS---------------------- 124
                                               |.|..|||
  Fly   131 SGHHRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNS 195

  Fly   125 ---------------------------VSEKSSSQPPAEESSNTNSTNHHNSSTNSNNNSKSETD 162
                                       |:.:.||.|.|..||..:||......|::|...|:|:
  Fly   196 NSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTES- 259

  Fly   163 HNESKGQSNSRTTSPGGASRASNDASHLYTSNKRPMPSDFGSDSLSIYSGKQLRRSLKDHGSGGS 227
               :|..|::...:.|.::.|:...:||:....:..     ||:::       ..:::....||:
  Fly   260 ---AKLTSSTAAPASGASASAAVQQAHLHQQQAQTT-----SDAIN-------TENVQAQSQGGA 309

  Fly   228 EGGGGDHAD----TAAGLDNSMNSEEFFLPPIPQITMGEQRYDLGGLKRESDGHHHGPLSAGGGN 288
            :|..||..|    :|.|..||.............:..|.....|..:..:|..:|...:     .
  Fly   310 QGVQGDDEDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKI-----K 369

  Fly   289 SGSVGSLTSS--ASPSAPIRNPFAPNFMDSFNY-----------YKGGNSSGPSGSSNNSVGPGG 340
            ..||.|:.|.  ..|.|...:......::....           ...|.|.|..|||........
  Fly   370 DNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQTYATWQH 434

  Fly   341 VNNNGSVGL-GSGAEYPNELYMPNDYSKSFANHMDIPSSGSNMVMLSTTSLLHGNCVFNRNNTVA 404
            ..:...:|| ...|:..:......|..:......|              .....:|:...|:.|.
  Fly   435 DRSQDELGLMAQDAQQRDPQASKQDKGEQTEGAQD--------------EFELDDCLLESNDIVI 485

  Fly   405 TQ--QGMKTYWLCKSYRISMCRARCITHLGRIISATGVHNHTPHMRGGQGSSAPSTASVSGNPAP 467
            ||  .|...:               :..||.|.:|....|.....:  ||.:|.:....:|.|.|
  Fly   486 TQNKDGFVLH---------------VKKLGNITAAKLEENQAVAQQ--QGQAAVTVTGPAGQPTP 533

  Fly   468 TPISSQAGYSLTDGGGHLGPDLQHGNRVTNMFANQTPPPPPPPPPL-PVASTP------------ 519
            |                          :|.:..........|.|.| .:.|||
  Fly   534 T--------------------------ITELLNAAAASHSEPKPTLTTLTSTPIKLPSSECELIN 572

  Fly   520 -------------HHPH------HHHHLGQPLPNLLVQHHPAPSHMEQHGSSASLLHNPNLMHLQ 565
                         ||||      |.||        ::||.....|.::|......:|...:.  |
  Fly   573 IKKIIPATTTIATHHPHTSSTIIHPHH--------IIQHVSQEPHHQEHHQQHQTIHIEEVP--Q 627

  Fly   566 TPTHHHQQQHHQQHSPHNPPPPQ-QHNLELGGGSGSGAVLLSPAHLQQS-PQSNRSSHSLQAQSP 628
            |...|||||||.|.....|...| |..:....|.....|.|....|..| |.::|..:|......
  Fly   628 TSQQHHQQQHHHQLQTVQPTHTQVQSIITAHPGQTINLVGLRNVQLADSKPIASRIRYSRGKIIG 692

  Fly   629 PP----QSVEEQQPHQQQQQQ-QEGATTEVT----TDPSTAHVINS 665
            |.    |.||..:|.|.|..: .:|...|::    .:|:.:..|.|
  Fly   693 PTVQNLQIVETHEPIQHQHHELSDGTKYEISEIDLNNPNASAAIIS 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34376	NP_732741.1	BTB_POZ_BAB-like	29..112	CDD:349624	38/82 (46%)
		FLYWCH	387..443	CDD:461332	10/57 (18%)
lola	NP_788308.3	BTB_POZ_BAB-like	31..114	CDD:349624	38/82 (46%)
		C2H2 Zn finger	905..925	CDD:275368
		zf-H2C2_5	935..957	CDD:404746
		C2H2 Zn finger	935..955	CDD:275368