DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and Clvs1

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	231	Identity:	53/231 - (22%)
Similarity:	102/231 - (44%)	Gaps:	11/231 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DPERVLAQVQDLSDWLVANPQINGCNTFENLHF-FLRTSKFDVERAKKKLKTFYQMRAERTEWFD 81
            :|:.:...:|.:.|.::..|.|....|.:.... |||..||....|.:.|..::|.|....:.|.
Mouse    45 NPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK 109

  Fly    82 NRDPQLPEIQDLLKLGVFLPI--GPDAEQRMVVVIRTAAHDPKLHSQNNVFKTSKMILDLLLKLD 144
            |.....|.|:..|..| |..:  ..|...|.::::..|..|...:|..::.:...:.|::|:: |
Mouse   110 NFKADDPGIKRALIDG-FPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIE-D 172

  Fly   145 PETCARGMVAILDMQGVQLGHALQMNPKLIKRSVES-WTAYPCQPKLLEFTNAPRHVNFFLNTFR 208
            ||....|.:.|:|........|.::.|.::|.::|. ..::|.:...:.|.|.|.:::......:
Mouse   173 PELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIK 237

  Fly   209 IFMTPKIRSRLFVRREGTS-----VSCDQLPKELGG 239
            .|:..|.|.|:|:.....:     :..:.||.|.||
Mouse   238 PFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGG 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	36/161 (22%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	12/45 (27%)
		CRAL_TRIO	125..274	CDD:366224	33/151 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820