DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and clvs2

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001020716.1	Gene:	clvs2 / 566769	ZFINID:	ZDB-GENE-041014-313	Length:	329	Species:	Danio rerio

Alignment Length:	263	Identity:	61/263 - (23%)
Similarity:	121/263 - (46%)	Gaps:	21/263 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DPERVLAQVQDLSDWLVANPQINGCNTFENLHF-FLRTSKFDVERAKKKLKTFYQMRAERTEWFD 81
            :|:.:...:|::.|.::..|.|....|.:.... |||..||:...|.:.|..:::.|.:..:.|.
Zfish    23 NPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFK 87

  Fly    82 NRDPQLPEIQDLLK---LGVFLPIGPDAEQRMVVVIRTAAHDPKLHSQNNVFKTSKMILDLLLKL 143
            |.....|.|:..||   .||...:  |...|.::|:..|..|...::..::.:...:.|:.:::
Zfish    88 NLKATDPGIKQALKDGFPGVLSNL--DRYGRKILVLFAANWDQSRYTFVDILRAILLSLEAMIE- 149

  Fly   144 DPETCARGMVAILDMQGVQLGHALQMNPKLIKRSVES-WTAYPCQPKLLEFTNAPRHVNFFLNTF 207
            |||....|.|.|:|........|.::.|.:::.::|. ..::|.:...:.|.|.|.:::......
Zfish   150 DPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVI 214

  Fly   208 RIFMTPKIRSRLFVRREGTSVSC-------DQLPKELGGQGLSYMELSVKWKQLVEENADFYVEQ 265
            |.|:..|.|.|:|:  .|.:::.       :.||.||||. |...::.. |.:.:.::|  |.|:
Zfish   215 RPFLKDKTRKRIFM--HGNNLNSLHQLILPEILPSELGGM-LPPYDMGT-WARTLLDHA--YDEE 273

  Fly   266 DKY 268
            ..|
Zfish   274 TDY 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	38/163 (23%)
clvs2	NP_001020716.1	CRAL_TRIO_N	29..75	CDD:215024	12/45 (27%)
		SEC14	106..251	CDD:238099	33/149 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820