DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and sec14l5

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_031749906.1	Gene:	sec14l5 / 493292	XenbaseID:	XB-GENE-953433	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	46/229 - (20%)
Similarity:	84/229 - (36%)	Gaps:	50/229 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ENLHFFLRTSKFDVERAKKKLKTFYQMRAER------TEWFDNRDPQLPEIQDLLKLGVFLPIG- 103
            |::..|||...|::::|::.|......|.:.      :.|    ||  |::     |..:...|
Frog   278 EHILRFLRARDFNIDKAREILCQSLTWRKQHHVDYLLSTW----DP--PQV-----LHDYYAGGW 331

  Fly   104 --PDAEQRMVVVIRTAAHDPKLHSQNNVFKT--SKMILDLLLKLDPETCAR-------------G 151
              .|.:.|.:.|:|....|.|     .:.:.  .:.:|..:|.::.|...|             .
Frog   332 HHHDRDGRPLYVLRLGQMDTK-----GLVRALGEESLLRHVLSINEEGLRRCEENTNIFGRPISS 391

  Fly   152 MVAILDMQGVQLGHALQMNPKLIKRSVESWTA-YPCQPKLLEFTNAPRHVNFFLNTFRIFMTPKI 215
            ...::|::|:.:.|..:...|.:.|.:|...| ||.....|....|||...........|:....
Frog   392 WTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDENT 456

  Fly   216 RSRLFVRR----EGTSVSCDQLPKE-----LGGQ 240
            |.:..:..    :|.....|.:.||     |||:
Frog   457 RKKFLIYAGNDYQGPGGLIDYIDKEVIPDFLGGE 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	34/180 (19%)
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	256..301	CDD:215024	7/22 (32%)
		CRAL_TRIO	326..490	CDD:395525	32/168 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910