DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	60/295 - (20%)
Similarity:	102/295 - (34%)	Gaps:	95/295 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 QVATTDGDP------ERVLAQVQDLSD--------WLVAN-----PQINGCNTFENLHFFLRTSK 56
            ::||.|||.      ||.|..:..:.:        ||...     |:      .|::..|||...
  Rat   217 EMATADGDKLDADYIERCLGHLSPMQESCLVQLRRWLQETHKGKIPK------DEHILRFLRARD 275

  Fly    57 FDVERAKKKLKTFYQMRAERTEWFDNRDPQLPEIQDLLKLGVFLPIGP------------DAEQR 109
            |.:::|:       .|..:...|  .:..|:    ||| |..:.|..|            |.:.|
  Rat   276 FHLDKAR-------DMLCQSLSW--RKQHQV----DLL-LQTWRPPAPLQEFYAGGWHYQDIDGR 326

  Fly   110 MVVVIRTAAHDPKLHSQNNVFKT--SKMILDLLLKLDPE-------------------TCARGMV 153
            .:.::|....|.|     .:.|.  .:.:|..:|.::.|                   ||
  Rat   327 PLYILRLGQMDTK-----GLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTC----- 381

  Fly   154 AILDMQGVQLGHALQMNPKLIKRSVE-SWTAYPCQPKLLEFTNAPRHVNFFLNTFRIFMTPKIRS 217
             :||::|:.:.|..:...|.:.|.:| ....||.....|....|||...........|:....|
  Rat   382 -LLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTR- 444

  Fly   218 RLFVRREGTS----------VSCDQLPKELGGQGL 242
            |.|:...|::          :..|.:|..|||:.:
  Rat   445 RKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGGESV 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	39/196 (20%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	25/111 (23%)
		CRAL_TRIO_N	243..288	CDD:215024	10/57 (18%)
		CRAL_TRIO	314..477	CDD:306996	33/174 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900