DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and Ttpa

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_037180.1	Gene:	Ttpa / 25571	RGDID:	3915	Length:	278	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	69/261 - (26%)
Similarity:	121/261 - (46%)	Gaps:	32/261 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RQVATTDGDPERVLAQVQDLSDWLVANPQINGCNTFENLHFFLRTSKFDVERAKKKLKTFYQMRA 74
            |:.|..:|.||    ..|.|:|..:..              |||...||::.|.:.:|.:|:.||
  Rat    32 RRRAQEEGVPE----TPQPLTDAFLLR--------------FLRARDFDLDLAWRLMKNYYKWRA 78

  Fly    75 ERTEWFDNRDPQLPEIQDLLKL---GVFLPIGPDAEQRMVVVIRTAAHDPKLHSQNNVFKTSKMI 136
            |..|...:..|:  .|..|||.   ||.....|...:  |::.|.:..|||:.:..:||:.|.:.
  Rat    79 ECPELSADLHPR--SILGLLKAGYHGVLRSRDPTGSR--VLIYRISYWDPKVFTAYDVFRVSLIT 139

  Fly   137 LDLLLKLDPETCARGMVAILDMQGVQLGHALQMNPKLIKRSVESWT-AYPCQPKLLEFTNAPRHV 200
            .:|::: :.||...|:.||.|::|.|:.||.|:.|.:.|:.....| ::|.:.:.:...|.|...
  Rat   140 SELIVQ-EVETQRNGVKAIFDLEGWQISHAFQITPSVAKKIAAVVTDSFPLKVRGIHLINEPVIF 203

  Fly   201 NFFLNTFRIFMTPKIRSRLFVRREGTSVSC-----DQLPKELGGQGLSYMELSVKWKQLVEENAD 260
            :...:..:.|:|.||:.|:.:.......|.     |.||.|.||...|..::..:|...:.::.|
  Rat   204 HAVFSMIKPFLTEKIKGRIHLHGNNYKSSLLQHFPDILPLEYGGNESSMEDICQEWTNFIMKSED 268

  Fly   261 F 261
            :
  Rat   269 Y 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	44/161 (27%)
Ttpa	NP_037180.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		CRAL_TRIO_N	25..73	CDD:215024	15/58 (26%)
		CRAL_TRIO	99..248	CDD:395525	40/151 (26%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000250\|UniProtKB:Q8BWP5	208..211		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1053004at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920