DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and Clvs2

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_780657.1	Gene:	Clvs2 / 215890	MGIID:	2443223	Length:	327	Species:	Mus musculus

Alignment Length:	271	Identity:	59/271 - (21%)
Similarity:	121/271 - (44%)	Gaps:	22/271 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DPERVLAQVQDLSDWLVANPQINGCNTFENLHF-FLRTSKFDVERAKKKLKTFYQMRAERTEWFD 81
            :|:.:...:|::.|.::..|.|....|.:.... |||..||....|.:.|..:::.|.:..:.|.
Mouse    23 NPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFK 87

  Fly    82 NRDPQLPEIQDLLKLGVFLPIG---PDAEQRMVVVIRTAAHDPKLHSQNNVFKTSKMILDLLLKL 143
            :.....|.|:..||.|  .|.|   .|...|.::|:..|..|...::..::.:...:.|:.:::
Mouse    88 SFKATDPGIKQALKDG--FPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIE- 149

  Fly   144 DPETCARGMVAILDMQGVQLGHALQMNPKLIKRSVES-WTAYPCQPKLLEFTNAPRHVNFFLNTF 207
            |||....|.|.|:|........|.::.|.:::.::|. ..::|.:...:.|.|.|.:::......
Mouse   150 DPELQVNGFVLIIDWSNFTFKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVI 214

  Fly   208 RIFMTPKIRSRLFVRREGTS-----VSCDQLPKELGGQGLSYMELSVKWKQLV-----EENADFY 262
            |.|:..|.|.|:|:.....:     :..:.||.|.||. |...::.. |.:.:     ::::::.
Mouse   215 RPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGM-LPPYDMGT-WARTLLDHEYDDDSEYN 277

  Fly   263 VEQDKYKSKLK 273
            |  |.|...:|
Mouse   278 V--DSYNMPVK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	37/161 (23%)
Clvs2	NP_780657.1	CRAL_TRIO_N	29..75	CDD:215024	12/45 (27%)
		SEC14	106..251	CDD:238099	30/145 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820