DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_446253.2	Gene:	Sec14l2 / 116486	RGDID:	621779	Length:	403	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	73/295 - (24%)
Similarity:	120/295 - (40%)	Gaps:	73/295 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ERVLAQV-QDLSDWLVANPQINGCNTFENLHFFLRTSKFDVERAKKKLKTFYQMRAER-----TE 78
            |..||:. :::.|.|.|.|  |..:.|  |..:||...||:::::..|:...:.|.::     ..
  Rat    13 EEALAKFRENVQDVLPALP--NPDDYF--LLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIIS 73

  Fly    79 WFDNRDPQLPE-IQDLL---KLGVFLP--------IGP-DAEQRMVV-----VIRTAAHDPKLHS 125
            |      |.|| ||..|   :.|..|.        ||| ||:..:..     ::||...|.:|..
  Rat    74 W------QPPEVIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLL 132

  Fly   126 QNNVFKTSKMILDLLLKLDPETCARGMVAILDMQGVQLGHALQMNPKLIKRSVESW--------T 182
            |....:|:|:...:      ||    :..|.|.:|:.|.|       |.|.:||::        .
  Rat   133 QECTHQTAKLGKKI------ET----ITMIYDCEGLGLKH-------LWKPAVEAYGEFLTMFEE 180

  Fly   183 AYPCQPKLLEFTNAPRHVNFFLNTFRIFMTPKIRSRLFVRREGTS--------VSCDQLPKELGG 239
            .||...|.|....||:......|..:.|::...|.::.|.  |.:        :|.||||.|.||
  Rat   181 NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVL--GANWKEVLLKHISPDQLPVEYGG 243

  Fly   240 QGLSYMELSVKWKQLVEENADF---YVEQDKYKSK 271
            . ::..:.:.|.|..:....|.   |..:|:.|.:
  Rat   244 T-MTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQ 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	48/186 (26%)
Sec14l2	NP_446253.2	CRAL_TRIO_N	13..59	CDD:215024	15/49 (31%)
		SEC14	76..244	CDD:214706	48/186 (26%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810