DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pinta and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001287466.1	Gene:	pinta / 42635	FlyBaseID:	FBgn0038966	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	281	Identity:	58/281 - (20%)
Similarity:	100/281 - (35%)	Gaps:	93/281 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 QVATTDGDPERVLAQVQD-LSDWLVANPQINGCNTFENLHF---FLRTSKFDVERAKKKLKTFYQ 71
            ||.......:..||:.:: |.|.|...|:.:.       :|   :||...||:::::..|:...:
Mouse     4 QVGDLSPQQQEALARFRETLQDLLPTLPKADD-------YFLLRWLRARNFDLKKSEDMLRKHVE 61

  Fly    72 MRAERT------------------------------EWFD---NRDPQLPEIQDLLKLGVFLPIG 103
            .|.::.                              .|||   ..||:          |:|:...
Mouse    62 FRNQQNLDQILTWQAPEVIQLYDSGGLSGYDYEGCPVWFDIIGTMDPK----------GLFMSAS 116

  Fly   104 -PDAEQRMVVVIRTAAHDPKLHSQNNVFKTSKMILDLLLKLDPETCARGMVAILDMQGVQLGHAL 167
             .|..::.:.|.....|:.:|.||....|..:|::                 :.||:|:.|.|
Mouse   117 KQDMIRKRIKVCEMLLHECELQSQKLGRKIERMVM-----------------VFDMEGLSLRH-- 162

  Fly   168 QMNPKLIKRSVESW--------TAYPCQPKLLEFTNAPRHVNFFLNTFRIFMTPKIRSRLFV--- 221
                 |.|.:||.:        ..||...|.|....||:......|..:.||..:.:.::.:
Mouse   163 -----LWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGG 222

  Fly   222 --RREGTS-VSCDQLPKELGG 239
              ::|... ||.||||.|.||
Mouse   223 NWKQELVKFVSPDQLPVEFGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pinta	NP_001287466.1	SEC14	87..240	CDD:238099	38/168 (23%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	12/52 (23%)
		SEC14	77..244	CDD:214706	43/201 (21%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810