Protein Alignment Nop56 and NOP56

DIOPT Version :10

• Sequence 1: NP_651040.3
• Gene: Nop56 / 42633
• FlyBaseID: FBgn0038964
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_006383.2
• Gene: NOP56 / 10528
• HGNCID: 15911
• Length: 594
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 307/493 - (62%)
• Similarity: 382/493 - (77%)
• Gaps: 11/493 - (2%)

  Fly     4 LYVLYEHAAGFSLFSVKEFEEVSMFLPQVESSVTDLAKFNSIVKLAGFAPFKTAIAALENINAIS 68
            |:||:|||.|::|.::||.||:|:..||||.||.:|.||:|||:|..|.||.::..||||.||:|
Human     4 LHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVS 68

  Fly    69 EGIVPQDLLSFLDDFFAKLKKKKCTLGIADAKLGAAITEAIGVQCSHFGVVPEILRGVRFHFAKL 133
            ||:|.:||...|:..... ||||..||:.|.|:||||.|.:|..|...||:.|||||||.||..|
Human    69 EGVVHEDLRLLLETHLPS-KKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNL 132

  Fly   134 VKGFTDKSAGVAQLGLGHSYSRAKVKFNVHRSDNMIIQSIALLDQLDKDVNTFSMRIREWYSYHF 198
            |||.||.||..||||||||||||||||||:|.||||||||:||||||||:||||||:||||.|||
Human   133 VKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHF 197

  Fly   199 PELVKIVPDNYMFAKAAKFIKDRKNLTQDQLEDLEKIVMDSAKAQAIIDAAKMSMGMDISIVDLM 263
            ||||||:.||..:.:.|:||.:|:.|.:|:||.||::.||.|||:||:||::.|||||||.:||:
Human   198 PELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLI 262

  Fly   264 NIELFAERVVKLSEYRKKLSTYLHNKMNLVAPNLQSLIGDQVGARLISHAGSLTNLAKYPASTVQ 328
            |||.|:.|||.|||||:.|.|||.:||:.|||:|.:|||:.||||||:|||||||||||||||||
Human   263 NIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQ 327

  Fly   329 ILGAEKALFRALKTRSNTPKYGLIYHSSFIGRAGLKNKGRISRFLANKCSIASRIDCFLEQPTSV 393
            |||||||||||||||.||||||||:||:|||||..||||||||:||||||||||||||.|.||||
Human   328 ILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSV 392

  Fly   394 FGETLKQQVEDRLKFYESGDVPRKNIEVMKEAIEAAGQEAAITVQSEKKKKKKKRAAEDEGETNG 458
            |||.|::|||:||.|||:|::||||::|||||:..| :|||..:..:.:|::|||..:::.....
Human   393 FGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQA-EEAAAEITRKLEKQEKKRLKKEKKRLAA 456

  Fly   459 ASNGNGAAAEAENGNGN----DDGEPKKKKKKKNKNKE 492
            .     |.|.:||.:..    ::...|.|||||.|.:|
Human   457 L-----ALASSENSSSTPEECEEMSEKPKKKKKQKPQE 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nop56	NP_651040.3	NOP5NT	5..70	CDD:462382	35/64 (55%)
		Nop	176..407	CDD:460335	169/230 (73%)
NOP56	NP_006383.2	NOP5NT	5..70	CDD:462382	35/64 (55%)
		Nop	175..405	CDD:460335	168/229 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..594		12/32 (38%)