DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lqfR and AT2G43160

DIOPT Version :9

Sequence 1:	NP_732736.2	Gene:	lqfR / 42632	FlyBaseID:	FBgn0261279	Length:	1415	Species:	Drosophila melanogaster
Sequence 2:	NP_001325306.1	Gene:	AT2G43160 / 818918	AraportID:	AT2G43160	Length:	895	Species:	Arabidopsis thaliana

Alignment Length:	579	Identity:	163/579 - (28%)
Similarity:	236/579 - (40%)	Gaps:	142/579 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VRELADKVTNVVMNYTETEGKVREATNDDPWGPTGPLMQELAYSTFSYETFPEVMSMLWKRMLQD 75
            ||:|..:|...|:.....|.||.:||:::||||.|.|:.:||.::.:|..:..:|.::||| |.|
plant     9 VRDLKREVNKKVLKVPGVEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMVVIWKR-LSD 72

  Fly    76 NKTNWRRTYKSLLLLNYLVRNGSERVVTSSREHIYDLRSLENYTFTDEGGKDQGINVRHKVRELI 140
            ...|||..||:|.:|.|:|.:|||||:...||..|.:.:|.::.:.|.||:|||.|||.|.:.|:
plant    73 TGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLV 137

  Fly   141 DFIQDDDRLREERKKAKKNKDKYIGMSSDAMGMRSGGYSG-YSGG------SGGGGGGSGGYNDG 198
            ..:.|.:|:.|.|:||..|:|||...:...|...||||.. |..|      |..|.....||.|.
plant   138 ALVNDKERIAEVRQKAAANRDKYRSSAPGGMYKPSGGYGDKYDYGSRDEERSSYGREREYGYRDD 202

  Fly   199 DYRSSRGDNWYSDKSADKDRY-----EDDDTHYDGEREGSDSDSPSPRRNYRYNDRASPAEVASE 258
            |..|..||....|   .:|||     .|||  |.|.....|        ||....|:|..|...:
plant   203 DRNSRDGDRHSRD---SEDRYGRDGNRDDD--YRGRSRSVD--------NYGSRGRSSEREREDD 254

  Fly   259 AKPSS-----------------LNMNIRSKTVSSPVSKQPTSTASAKPALSQKKIDLGAAANFGK 306
            ...||                 |......:.:.:|.|.:...:.|..|..|::
plant   255 GHSSSRGSGARADDNSQDGRGGLQRKFSEQNIGAPPSYEEAVSDSRSPVYSER------------ 307

  Fly   307 PAPGGAAGIHSPTHRDTPTSVDLMGGASPSPSTSKANNNTQSNNNDLLDDLFKTCSPPPGQEKTL 371
              .||          :|| .|...|.|||.|....|.               :..|||.| ..|.
plant   308 --DGG----------ETP-QVTAPGAASPPPPQVAAP---------------EAASPPTG-TNTA 343

  Fly   372 NSAAVIVDDD--------DDFNPRASDASQQEFGDFASAF--GQPSAGST--ISEPPSTGLVPA- 423
            |:.|..|::.        |:|:||             |||  |.|:..||  ::.||:...:.|
plant   344 NTTATFVNESPSQKVETFDEFDPR-------------SAFSAGPPAYASTDGVTAPPTVTSMSAP 395

  Fly   424 --ANDEFADFAAFQGSTTSTSAL------------DGNL-------LKTATPANDSF-DLFNSAP 466
              :|....|.........|::||            :|..       ..|:.|:..|| |.|..:|
plant   396 TTSNSVEMDLLGSLADVFSSNALAIVPADSIYVETNGQANAGPAPSFSTSQPSTQSFDDPFGDSP 460

  Fly   467 TSTAAATTATDLLAGLGDLSIHQSMPMAVEEQLASSN--------DSMSS-ASPQPPSE 516
            .. |..:|.||........:..|..|.|...:::..:        ||.|: |:|.|.|:
plant   461 FK-AFTSTDTDSTPQQNFGASFQPPPPAFTSEVSHPDTAHNFGFGDSFSAVANPDPASQ 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lqfR	NP_732736.2	ENTH_epsin	27..150	CDD:239627	51/122 (42%)
		DUF4045	<226..459	CDD:289995	57/283 (20%)
		Telomere_reg-2	1072..1184	CDD:287202
AT2G43160	NP_001325306.1	ENTH	26..142	CDD:340772	49/116 (42%)
		PRK12678	142..>280	CDD:237171	44/150 (29%)
		PHA03247	<366..707	CDD:223021	39/167 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3473
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12276
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010